Publications by authors named "MEJIA C"

Integrated health and nutrition packages in schools have been shown to be a cost-effective approach to support children's well-being and academic achievement; yet few countries adequately invest in promoting such integration. School feeding programmes in Latin America are among the best-established, with some of the largest scale and coverage in the world. National School Meal programmes in Latin America and the Caribbean benefit over 80.

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Patent analytics is crucial for understanding innovation dynamics and technological trends. However, a comprehensive overview of this rapidly evolving field is lacking. This study presents a data-driven analysis of patent research, employing citation network analysis to categorize and examine research clusters.

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Introduction: Resentment towards the Chinese population was perceived during the first months of the pandemic because the pandemic/disease started in that country.

Objective: To determine the factors associated with the perception of resentment towards the Chinese in Latin America during the first wave of the COVID-19 pandemic.

Methodology: Analytical cross-sectional study conducted during the second semester of the pandemic in more than a dozen countries.

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Background: Motivation for the study. There are few clinical and survival studies in Peru on thyroid cancer.

Background: Main findings.

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Article Synopsis
  • The study investigates a specific genetic variant in the IP3 receptor that results in a significant disorder affecting multiple systems, characterized by immunodeficiency and disturbed calcium release in cells.
  • The variant (c.7570C>T, p.Arg2524Cys) leads to cellular defects, particularly impacting T cells, and is shown to affect calcium regulation and mitochondrial function, evidenced in laboratory models.
  • Patients exhibited a range of symptoms beyond immunodeficiency, such as ectodermal dysplasia and short stature, suggesting that this genetic mutation plays a unique and broader role in disease compared to previously documented cases.
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It is important for providers caring for kidney transplant recipients to be familiar with the common causes of allograft dysfunction. Early detection of allograft dysfunction leads to timely management, with the goal of preventing or delaying progression to allograft failure. Although transplant rejection is always a concern, the differential diagnoses for allograft dysfunction are broad and include perioperative complications, infections, recurrent disease, and calcineurin nephrotoxicity.

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In order to meet the climate goals of the Paris Agreement and limit the potentially catastrophic consequences of climate change, we must move away from the use of fossil feedstocks for the production of chemicals and fuels. The conversion of synthesis gas (a mixture of hydrogen, carbon monoxide and/or carbon dioxide) can contribute to this. Several reactions allow to convert synthesis gas to oxygenates (such as methanol), olefins or waxes.

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Triple-negative breast cancer (TNBC), accounting for 15-20% of all breast cancers, has one of the poorest prognoses and survival rates. Metastasis, a critical process in cancer progression, causes most cancer-related deaths, underscoring the need for alternative therapeutic approaches. This study explores the anti-migratory, anti-invasive, anti-tumoral, and antimetastatic effects of copper coordination compounds Casiopeína IIIia (CasIIIia) and Casiopeína IIgly (CasIIgly) on MDA-MB-231 and 4T1 breast carcinoma cell lines in vitro and in vivo.

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Introduction: Living kidney donor evaluation is a lengthy and complex process requiring in-person visits. Access to transplant centers, travel costs, lost wages, and dependent care arrangements are barriers to willing donors initiating evaluation. Telemedicine can help streamline and epedite the evaluation process.

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This study aimed to isolate and characterize a native strain of Beauveria bassiana, coded as Bv065, showcasing its potential as a biological control agent targeting the palm weevil Dynamis borassi. Originating from a naturally infected D. borassi specimen collected in southwestern Colombia, the fungus underwent molecular identification and was identified as B.

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The application of enzymes in agricultural fields has been little explored. One potential application of fungal lytic enzymes (chitinases, lipases, and proteases) is as an additive to current biopesticides to increase their efficacy and reduce the time of mortality. For this, a screening of lytic overproducer fungi under submerged fermentation with a chemical-defined medium was performed.

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Background: More than 700,000 people suffer from vertebral compression fractures attributed to osteoporosis, metastatic disease, or trauma each year in the United States, and undergo kyphoplasty. They are typical. These often undergo kyphoplasty to treat resultant pain or new neurological deficits.

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: climate change is a reality, and more and more people are becoming aware of this global problem, which has generated anxiety in some populations. To validate a short survey to assess eco-anxiety in adults in South America. : It is an instrumental study, and the validation was based on a previous survey, which had six questions and was generated by 217 respondents in the USA in 2021.

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The concentration of gases in the atmosphere is a topic of growing concern due to its effects on health, ecosystems etc. Its monitoring is commonly carried out through ground stations which offer high precision and temporal resolution. However, in countries with few stations, such as Ecuador, these data fail to adequately describe the spatial variability of pollutant concentrations.

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This study aimed to analyze the effect of nutritional supplements on improving conidia production of Nm017 at laboratory scale (yields of conidia/substrate and biomass/substrate, and substrate consumption). Also, the influence on quality parameters were evaluated (germination at 36 and 48 h, enzymatic activity, and insecticidal activity on ). Six treatments (T1-T6) were assessed and all of them reached maximum conidia concentration after 7 days fermentation, a feasible production timetable.

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This study investigates the effectiveness of a computerized cognitive test battery embedded within a video game to assess executive functions (EF) in deaf and hearing children. We evaluated a diverse cohort of 290 elementary school students aged 5 to 13 years (mean age = 8.86, SD = 1.

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Article Synopsis
  • - The study aims to create new pulse oximetry screening (POS) algorithms for critical congenital heart disease (CCHD) suitable for high-altitude conditions, where existing algorithms are ineffective.
  • - Conducted in Peru, the research involved 502 healthy newborns and 15 with CCHD, incorporating oximetry tests and follow-ups to assess the effectiveness of the algorithms.
  • - Two new algorithms were developed, showing one with high sensitivity (92%) but lower specificity (73%), while the other maintained a balance with lower sensitivity (80%) and higher specificity (88%), although both faced challenges with false positives.
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Introduction: Latin America was the region most affected by COVID-19 in the second quarter of 2020, and consequently, the impact on mental health requires evaluation. The aim of this study was to assess the risk of post-traumatic stress disorder (PTSD) caused by bereavement due to COVID-19 in 12 countries in Latin America.

Methods: The current study was an analytical cross-sectional study.

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Introduction: The coronavirus disease 2019 (COVID-19) pandemic has triggered a rise in the global phenomenon of self-medication. The use of medicines with unsubstantiated claims of benefit for the prevention and/or treatment of infected people has been widely adopted.

Objective: To determine the factors associated with the use of medicines and self-medication by Latin American populations during the COVID-19 pandemic.

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Introduction And Objectives: Burnout syndrome (BS) has been evaluated in few populations of medical students, and its relationship with depression is even less studied. The objective was to determine the frequency of BS in medical students of the Universidad Pedagógica y Tecnológica de Colombia (UPTC), in Tunja, Colombia, as well as its association with depression and other social, economic, demographic, and academic factors.

Methods: An observational, analytical, cross-sectional study was carried out on 182 UPTC medical students during 2018.

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Neuroblastoma represents a neoplastic expansion of neural crest cells in the developing sympathetic nervous system and is childhood's most common extracranial solid tumor. The heterogeneity of gene expression in different types of cancer is well-documented, and genetic features of neuroblastoma have been described by classification, development stage, malignancy, and progression of tumors. Here, we aim to analyze RNA sequencing datasets, publicly available in the GDC data portal, of neuroblastoma tumor samples from various patients and compare them with normal adrenal gland tissue from the GTEx data portal to elucidate the gene expression profile and regulation networks they share.

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Background: COVID-19 mRNA vaccines play a vital role in the fight against SARS-CoV-2 infection. However, lactating women have been largely excluded from most vaccine clinical trials. As a result, limited research has been conducted on the systemic distribution of vaccine mRNA during lactation and whether it is excreted in human breast milk (BM).

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Article Synopsis
  • The research analyzed the phytochemical composition and metabolomics of two edible plants, CA and PR, which are traditional food sources in Mexico, to evaluate their antiproliferative effects on cancer cells.
  • Using advanced techniques, 38 polyphenols and certain organic acids were identified and linked to metabolic activities such as indolizidines and pyridines.
  • CA showed a stronger reduction in cancer cell activity compared to PR, while both extracts caused increased cell apoptosis and cell cycle arrest, indicating potential for cancer treatment, but more studies on different cell lines are needed.
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Background: Routine screening for social determinants of health (SDOH) in the outpatient oncology setting is uncommon. The primary goal of this study was to prospectively evaluate the feasibility and acceptability of implementing an electronic health record (EHR) SDOH screening instrument into routine, clinical, oncology practice.

Methods: Adult patients with newly diagnosed gastrointestinal cancer presenting to a regional cancer center (November 2020 to July 2021) were eligible.

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