Publications by authors named "MATUSZEWSKI M"

: Kidney cancer accounts for approximately 2% of all diagnosed cancers and fatalities worldwide, and a notable increase in its incidence has been observed in recent years. Previous studies have identified various risk factors for renal cell carcinoma (RCC), including age, gender, smoking, hypertension, overweight, and obesity. However, limited information is available regarding the correlation between RCC risk factors and tumor lateralization.

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Exploring the non-Hermitian properties of semiconductor materials for optical applications is at the forefront of photonic research. However, the selection of appropriate systems to implement such photonic devices remains a topic of debate. In this work, we demonstrate that a perovskite crystal, characterized by its easy and low-cost manufacturing, when placed between two distributed Bragg reflectors with an air gap, can form a natural double microcavity.

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Introduction: Oral mucosal grafts are essential in reconstructive urology, particularly for urethral and genital defects. Advances in harvesting and implantation techniques have been made, yet perioperative care remains crucial for optimal outcomes. This systematic review explores postoperative care pathways following oral mucosal graft harvesting to consolidate knowledge, identify best practices, and highlight research gaps.

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Background: Penile cancer is a relatively rare neoplasm in developed countries, with the majority of newly diagnosed cases presenting as organ-confined, with a 5-year survival rate of 90%. Therefore, it is crucial to consider the impact of penile tumor resection on sexual and urinary function. Regrettably, the literature is devoid of comprehensive, step-by-step video instructions for the surgical procedure of partial penectomy with reconstruction using a split-thickness skin graft (0.

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  • Liquid biopsies, especially focusing on circulating tumor cells (CTCs) in blood, provide crucial insights into cancer spread, but current analysis is mainly limited to counting and basic marker profiling.
  • A study analyzed CTCs' size, shape, and features from different cancers using advanced imaging methods, finding notable size and shape differences among at least four different cell types.
  • Findings revealed that lung cancer produced the largest CTCs, while prostate and breast cancers had smaller ones, and distinct characteristics in cell shape corresponded to their epithelial or mesenchymal origins.
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Introduction: The aim of this study was to retrospectively evaluate the etiology of urethral stricture disease (USD) in a large series of patients undergoing urethroplasty.

Material And Methods: The multicenter retrospective cohort study was conducted at two reconstructive urology referral centers in years 2015-2022. Prior to the surgical intervention, all patients underwent diagnostic procedures including retrograde urethrography and voiding cystourethrography.

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  • Micronuclei (MN) are formed through various mechanisms, and their frequent presence in tumors suggests they might actively contribute to cancer progression rather than being just passive byproducts.
  • This study highlights how damages during cell division can lead to the accumulation of Emerin in MN, which lack Lamin A/C and feature the Lamin-B receptor and Sec61β.
  • Emerin mislocalization to MN is linked to a poor prognosis in prostate cancer patients and is associated with increased migratory and invasive behaviors of tumor cells, particularly in environments rich in collagen.
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Perovskite crystals-with their exceptional nonlinear optical properties, lasing and waveguiding capabilities-offer a promising platform for integrated photonic circuitry within the strong-coupling regime at room temperature. Here we demonstrate a versatile template-assisted method to efficiently fabricate large-scale waveguiding perovskite crystals of arbitrarily predefined geometry such as microwires, couplers and splitters. We non-resonantly stimulate a condensate of waveguided exciton-polaritons resulting in bright polariton lasing from the transverse interfaces and corners of our perovskite microstructures.

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Background: Evaluating outcomes of concurrent Cox-Maze procedures in elderly patients undergoing high-risk cardiac surgery.

Mehods: We retrospectively identified patients aged over 70 years with Atrial Fibrillation (AF) from 2011 to 2017 who had two or more other cardiac procedures. They were subdivided into two groups: 1.

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Buschke-Löwenstein tumor (BLT), also called giant condyloma acuminatum is a rare clinical manifestation caused by human papillomavirus (HPV), usually type 6 or 11 (90 %). The BLT is described as a tumor with localized aggressiveness, rather slow but destructive and invasive growth of surrounding tissues, benign histology, low metastatic potential, and a high tendency of recurrence. We present the case of a 55-year old non-immunocompetent man, with beige, cauliflower-like papillomae presented on glans penis and coronal sulcus which increased in size for a few weeks.

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Multi-parametric prostate MRI (mpMRI) is crucial for diagnosing, staging, and assessing treatment response in individuals with prostate cancer. Radiologists, through an accurate and standardized interpretation of mpMRI, stratify patients who may benefit from more invasive treatment or exclude patients who may be harmed by overtreatment. The integration of prostate MRI into the diagnostic pathway is anticipated to generate a substantial surge in the demand for high-quality mpMRI, estimated at approximately two million additional prostate MRI scans annually in Europe.

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Introduction: The study presents the initial outcomes of robot-assisted radical prostatectomies (RARPs) using the Versius robotic system in a urological centre with no prior robotic surgery experience.

Material And Methods: A retrospective analysis of 58 RARPs was conducted, including patients' parameters as well as Versius system performance.

Results: The study involved 58 patients (average age 66.

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Bladder urothelial carcinoma (BLCA) is the 10th most common cancer with a low survival rate and strong male bias. We studied the field cancerization in BLCA using multi-sample- and multi-tissue-per-patient protocol for sensitive detection of autosomal post-zygotic chromosomal alterations and loss of chromosome Y (LOY). We analysed 277 samples of histologically normal urothelium, 145 tumors and 63 blood samples from 52 males and 15 females, using the in-house adapted Mosaic Chromosomal Alterations (MoChA) pipeline.

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  • Posterior hypospadias is a serious congenital condition that significantly impacts patients' lifelong quality of life and presents ongoing surgical challenges, leading to complications through adulthood.
  • A network meeting in Utrecht aimed to identify gaps in the lifelong treatment approach for these patients, focusing on improving care, quality of life, and awareness.
  • Critical recommendations include enhancing patient involvement in treatment decisions, standardizing data collection at a European level, and fostering collaboration among researchers, clinicians, and patients to explore innovative solutions like tissue engineering.
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Purpose: To synthetize the current scientific knowledge on the use of ultrasound of the male urethra for evaluation of urethral stricture disease. This review aims to provide a detailed description of the technical aspects of ultrasonography, and provides some indications on clinical applications of it, based on the evidence available from the selected prospective studies. Advantages and limitations of the technique are also provided.

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Kidney renal clear cell carcinoma (KIRC) is the most common type of kidney cancer and its pathogenesis is strongly associated with VHL-HIF-VEGF signaling. SHH ligand is the upstream SHH pathway regulator, while GLI1 is its major effector that stimulates as a transcription factor, i.a.

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Penile cancer is a rare neoplasm in developed countries with an incidence of 0.8/100,000 per male inhabitant. Despite the development of personalized medicine and multimodal treatment, the outcome of penile cancer treatment is insufficient.

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Background: Airway management in life-threatening emergencies is essential for children, and endotracheal intubation is the gold standard. It protects against regurgitation and enables mechanical ventilation. New types of airway management equipment are being developed and implemented to meet the needs of medical personnel.

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  • Multiparametric prostate MRI (mpMRI) is increasingly recommended for diagnosing and monitoring prostate cancer, but it can produce false positives and negatives due to overlapping anatomical structures and benign conditions.
  • This review highlights common misinterpretations, including normal anatomical features and benign issues like benign prostatic hyperplasia (BPH) that may mimic cancer signs.
  • The authors emphasize the importance of recognizing these pitfalls and ensuring high-quality imaging to enhance diagnostic accuracy for radiologists.
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  • Penile metastasis is very rare, primarily associated with bladder and prostate cancers.
  • Diagnosis usually starts with penile symptoms but often leads to the discovery of metastasis in other organs, worsening patient outcomes.
  • A case study of an 80-year-old patient revealed high-grade urothelial cancer during circumcision, highlighting the use of CT scans in identifying widespread cancer.
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  • - Onco-nephrology is an emerging medical field that explores the relationship between kidney issues in cancer patients and cancer occurrences in those with kidney diseases.
  • - The focus is on understanding acute kidney injury (AKI), chronic kidney disease (CKD), and related complications like electrolyte imbalances in the context of cancer treatment.
  • - The article discusses how assessing kidney function can help optimize chemotherapy and highlights the potential of new cancer therapies, including immunotherapy, for patients with transplants.
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Introduction And Objective: In COVID-19, the rapid prediction of the severity of a patient's condition using modern biomarkers can accelerate the implementation of appropriate therapy, and thus improve the patient's prognosis.

Material And Methods: A meta-analysis was conducted of data available in the literature on the differences in baseline suPAR blood concentration between patients (1) who tested positive and negative for COVID-19, (2) who had severe and non-severe COVID-19, and (3) COVID-19 survivors and non-survivors.

Results: SuPAR levels in SARS-CoV-2 negative and positive patients varied and amounted to 3.

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  • The study aimed to compare diffusion kurtosis imaging (DKI) and the standard monoexponential (ME) apparent diffusion coefficient (ADC) model for detecting significant prostate cancer using whole-mount histopathology as a reference.
  • It involved 155 prostate cancer patients who underwent multiparametric MRI, analyzing various diffusion parameters like D, K, and ADC and correlating them with Gleason scores.
  • Results showed significant differences in diffusion parameters between malignant and benign tissues, but both DKI and ADC models performed similarly in diagnosing prostate cancer, indicating no clear advantage of the kurtosis model over the standard ADC method.
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  • The COVID-19 pandemic significantly affected surgical training globally, particularly in reconstructive urology, as resources were shifted to prioritize urgent medical needs.
  • The lack of practical training during this period has resulted in gaps in the skills needed for future urologists.
  • To overcome these challenges, the integration of virtual reality technologies is proposed as an essential tool for enhancing education and training in reconstructive urology surgery.
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