[The complex immunological examination of tuberculous patients (author's transl)].

The significance of immunological reactivity in tuberculosis was investigated in 325 patients with various forms of pulmonary tuberculosis (disseminated, destructive, severe, treated, and not yet treated forms) for T-lymphocytes with the aid of the spontaneous rosette formation, the lymphocytes transformation test ot phytohaemagglutinin, and the determination of the lymphocyte sensibility to cortisol; for the B-lymphocytes with the aid of complement rosette formation, the determination of immunoglobulins M, G, A, and the heterophile agglutinins; for the evaluation of the intensity of tuberculin allergy by the cutaneous test, the lymphocyte transformation test, the leucocyte migration inhibition test, the neutrophils toxicity test to tuberculin, and the passive haemagglutination. These investigations revealed a considerable impairment of the immunological reactivity in dependence of disease pattern and duration.

[Significance of immunological investigation in pulmonary pathology].

An extensive range of investigations were used in a comparative study of immune reactivity in the tuberculous pulmonary pathology, as well as in sarcoidosis, pneumonia and cancer of the lungs. T and B lymphocyte populations were followed, indexes of leucocyte migration, induced lymphoblastogenesis to phytohaemagglutinin, and the serum levels of immunoglobulins. Also the intensity of the hypersensitivity to tuberculin was investigated, to allergens extracted from staphylococcus and streptococcus strains, as well as against organ antigens (pulmonary tissues).