[Mental illness in former residents affected by the extraction of rock salt from a mining company in Maceió, Alagoas State, Brazil].

This study aimed to investigate the presence of mental illness in victims of soil instability in neighborhoods affected by rock salt extraction from a mining company located in the city of Maceió, Alagoas, Brazil. It is a quantitative, descriptive-analytical, and cross-sectional study. The sample was intentional and non-probabilistic and consisted of 158 participants, with a 0.

[Neighborhood characteristics in Belo Horizonte, Minas Gerais State, Brazil: an intraurban analysis using systematic social observation method].

Systematic social observation (SSO) is an objective method of measuring the neighborhood physical and social characteristics. This study aimed to build intraurban indicators using the SSO method and compare them between two slums and their surroundings in a Brazilian capital. The simple indicators were calculated using the ratio estimator method, and grouped into domains.

Neurophysiological gradient in the Parkinsonian subthalamic nucleus as a marker for motor symptoms and apathy.

Sensing-based deep brain stimulation should optimally consider both the motor and neuropsychiatric domain to maximize quality of life of Parkinson's disease (PD) patients. Here we characterize the neurophysiological properties of the subthalamic nucleus (STN) in 69 PD patients using a newly established neurophysiological gradient metric and contextualize it with motor symptoms and apathy. We could evidence a STN power gradient that holds most of the spectral information between 5 and 30 Hz spanning along the dorsal-ventral axis.

Impulse Control Disorders and Effort-Based Decision-Making in Parkinson's Disease Patients with Subthalamic Nucleus Deep Brain Stimulation.

Background: Impulse control disorders (ICD) are common side effects of dopaminergic treatment in Parkinson's disease (PD). Whereas some studies show a reduction in ICD after subthalamic nucleus deep brain stimulation (STN-DBS), others report worsening of ICD or impulsivity.

Objective: The aim was to study ICD in the context of STN-DBS using an objective measure of decision-making.

Two novel variants in associated with anophthalmia and congenital cystic eye.

Purpose: We present the case of a newborn with right anophthalmia, left congenital cystic eye, and two novel variants in the gene. This report provides a comprehensive discussion of the clinical presentation, management strategies, and long-term follow-up for this rare condition.

Methods: A thorough ophthalmic examination was performed.

High-intensity interval training improves hepatic redox status via Nrf2 downstream pathways and reduced CYP2E1 expression in female rats with cisplatin-induced hepatotoxicity.

Cisplatin (CP) is an antineoplastic drug associated with various cytotoxic adverse effects, including hepatotoxicity. Exercise training may offer hepatoprotection by improving redox status. This study compared the effects of light-intensity continuous training (LICT), moderate-intensity continuous training (MICT), and high-intensity interval training (HIIT) on CP-induced hepatotoxicity in female Wistar rats.

Exploring the effects of climate change on child malnutrition: protocol for a scoping review.

Introduction: Rapid climate changes in the early 21st century have triggered a global syndemic intertwining obesity, undernutrition and climate change, profoundly affecting health, especially children. Despite increasing research, a significant gap persists in understanding the mechanisms linking climate change to child malnutrition, particularly in children under 5 years old. This protocol proposes a scoping review to address this gap, with the aim of mapping the available evidence on the relationship between climate change and malnutrition among children under 5 years old.

Protocols for Postanesthesia Care Unit Handoff and Patient Safety: A Scoping Review.

Aim: To map studies that tested an intervention orienting patient transfer to Postanesthesia Care Unit (PACU) and identify outcomes related to care safety.

Methods: Scoping review guided by recommendations of the JBI Manual and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) guide. The Population, Concept, and Context (PCC) framework was used to develop the research question and consolidate inclusion and exclusion criteria in databases consulted without date parameters.

The nursing practice environment and hospital sociotechnical complexity: a mixed-methods study.

Objectives: to analyze the relationship between the nursing practice environment and hospital sociotechnical complexity as perceived by nurses.

Methods: a sequential explanatory mixed-methods study was conducted in a hospital in southern Brazil. The Brazilian version of the Practice Environment Scale-Nursing Work Index and the Complexity Characterization Questionnaire were administered to 132 nurses.

Educational technology to support patient safety in the operating room: clinical simulation guides.

to develop and validate two clinical simulation guides to support and disseminate a culture of safety in the surgical environment. methodological study supported by the International Nursing Association for Clinical Simulation and Learning theoretical framework. The snowball technique was used to validate the clinical guidelines with experts on the subject.

Efficacy and safety of TiF varnish in preventing erosive tooth wear in a rat animal model.

An animal model was applied to develop erosive tooth wear (ETW) and to evaluate the efficacy and safety of titanium tetrafluoride (TiF) in preventing ETW. Forty-eight male Wistar rats were divided into three groups (n = 16): TiF (2.45% F), NaF (2.

Portuguese translation, cultural adaptation and psychometric properties of the temporomandibular joint scale: a cross-sectional study.

Background: The temporomandibular joint (TMJ) scale assesses the severity of temporomandibular joint disorders (TMD), yet a European Portuguese translation is lacking.

Objectives: To translate, cross-culturally adapt and to examine the psychometric properties (construct validity and reliability) of the TMJ scale.

Methods: Translation and cultural adaptation were carried out according to international recommendations, including initial translation, evaluation of this translation and cultural adaptation by a panel of experts, and back translation.

Novel Fundoscopic Features in Mucopolysaccharidosis Type VI: Multimodal Evaluation of Scleral Deposits.

Introduction: Mucopolysaccharidosis type VI (MPS VI) is a rare inherited metabolic disorder, primarily attributed to the deficiency of the enzyme N-acetylgalactosamine-4-sulfatase, responsible for the degradation of dermatan sulfate and chondroitin-4-sulfate. Therefore, there is a widespread accumulation of partially degraded glycosaminoglycans. Corneal opacification is the hallmark ocular feature in the MPS.

Evaluation of Tissue Biocompatibility of Calcium Silicate-based and Epoxy Resin-based Sealers.

Introduction: Calcium silicate-based sealers are an alternative to be used into root canal, mainly to their biological properties. However, some biological parameters need to be determined in an animal research model. So, the aim of the present study was to evaluate the tissue biocompatibility of a calcium silicate-based sealer (EndoSequence BC Sealer) and an epoxy resin-based sealer (AH-Plus).

Ste2 and Ste3 receptors undergo peroxidase-induced heterodimerization when expressed heterologously in .

Ste2 and Ste3 are G-protein-coupled receptors (GPCRs) shown to play roles in hyphal chemotropism and fungal plant pathogenesis in response to activity arising from host-secreted peroxidases. Here, we follow up on the observation that chemotropism is dependent on both Ste2 and Ste3 being present; testing the possibility that this might be due to formation of an Ste2-Ste3 heterodimer. Bioluminescence resonance energy transfer (BRET) analyses were conducted in , where the addition of horse radish peroxidase (HRP) was found to increase the transfer of energy from the inducibly expressed Ste3-Nano luciferase donor, to the constitutively expressed Ste2-yellow fluorescent protein (YFP) acceptor, compared to controls.

Investigating the distribution of a unique crustacean microendemic to tree hollows.

Water-filled tree hollows constitute phytotelmata that harbor specialized organisms. One striking example of extreme adaptation to these microhabitats is the case of the microcrustacean Micromoina arboricola, which has been found inhabiting the hollow of a single tree individual in the Atlantic Forest. We investigated the spatial distribution and influence of microhabitat characteristics such as hollow volume and height from the ground in the occurrence of M.

Sarcosine, Trigonelline and Phenylalanine as Urinary Metabolites Related to Visceral Fat in Overweight and Obesity.

The objective of the present study is to analyze the urinary metabolome profile of patients with obesity and overweight and relate it to different obesity profiles. This is a prospective, cross-sectional study in which patients with a body mass index (BMI) ≥25 kg/m were selected. Anthropometric data were assessed by physical examination and body composition was obtained by bioimpedance (basal metabolic rate, body fat percentile, skeletal muscle mass, gross fat mass and visceral fat).

Bleaching as a complement to fluoride-enhanced remineralization or resin infiltration in masking white spot lesions.

Objective: There are many suitable strategies for addressing caries, which is an ongoing worldwide problem. Although white spot lesions (WSLs) can be either remineralized naturally or treated with non- or micro-invasive strategies, their whitish and opaque appearance may persist. To evaluate the effects of tooth bleaching as a complement to fluoride-enhanced remineralization or resin infiltration in masking WSLs, as well as in enamel surface roughness relative to that of the adjacent enamel.

High-intensity interval training alleviates liver inflammation by regulating the TLR4/NF-κB signaling pathway and M1/M2 macrophage balance in female rats with cisplatin hepatotoxicity.

Cisplatin (CDDP) is an antineoplastic drug whose adverse effects include hepatotoxicity. The inflammatory process is crucial in the progression of liver injuries. Exercise is known for its anti-inflammatory effects, but the influence of different training modalities on hepatoprotection is still unclear.

Food and fluid intake during labor in maternity wards: A scoping review protocol.

During the 1940s, aspiration of stomach contents was recognized as a serious problem during labor, which is why fluid and food restriction was adopted for women who would undergo general anesthesia. Currently, the practice of generalized food restriction is a routine that is being discontinued. This review aims to map the evidence on the effects of the intake of foods, supplements and drinks in women on labor outcomes.

Influence of irradiated dentin, biofilm and different artificial saliva formulations on root dentin demineralization.

The aim of this study was evaluated the influence of radiation as well as of new formulations of artificial saliva on the development of root dentin lesions. Bovine root samples were divided into: irradiated (70 Gy) dentin or not; the type of biofilm (from irradiated patient-experimental or non-irradiated patient-control) and the type of artificial saliva (for the condition irradiated dentin/biofilm from irradiated patient): Control Artificial Saliva (inorganic); Control Saliva + 1 mg/ml hemoglobin; Control Saliva +0.1 mg/ml cystatin; Control Saliva + hemoglobin + cystatin; Bioextra (positive control) and deionized water (DiW, negative control) (n = 12/group).

Behavioural changes of native freshwater prawn in the presence of a predator fish.

Predation pressure influences animal behaviour in relation to feeding, exposure to predators and habitat use. In the presence of a predator, prey usually decreases feeding and activity, avoiding predation-risk areas. This study evaluated the visual effects of a predator fish (red-bellied piranha Pygocentrus nattereri) on the behaviour and habitat use of Macrobrachium jelskii prawn.

[Prevalence of the use of integrative and complementary practices and chronic diseases: 2019 National Health Survey].

The study sought to investigate the association between having a chronic disease or condition and the prevalence of having recourse to Integrative and Complementary Practices (ICP) among the Brazilian adult population. Chronic diseases are a serious public health issue and there are limitations of Western medicine to offer effective answers. Thus, the demand for ICP has increased as they constitute a humanized treatment option, with low cost and ease of acquisition.