Publications by authors named "MACCHI L"

The current study aimed to fill the gap in research on factors predictive of word reading in French-speaking children with developmental language disorder (DLD) by finding out whether the same predictors of written word recognition evidenced in typically developing children would be retrieved in children with DLD or if some predictors could be specific to children with DLD, especially in the phonological domain. In total, 38 children with DLD and 44 control children were followed from 6 to 8 years in a longitudinal design including two time points: (1) just before explicit reading instruction, where potential predictors of reading were assessed (oral language skills and reading-related skills), and (2) after 2 years of learning to read, where isolated word reading and text reading were assessed in addition to the assessment of oral language skills and reading-related skills. The study mainly showed that the predictors of reading identified in typically developing children are retrieved in children with DLD except for phonemic awareness; the latter result was probably explained by a floor effect.

View Article and Find Full Text PDF

Roselle ( L.) is a worldwide known species of great importance due to its medicinal properties and pleasant flavor. In Paraguay, it is used as an alternative crop by family-run farmers; however, the varieties used in the country are unknown, so no information is available on this crop.

View Article and Find Full Text PDF

Although two clusters have been identified in France, constitutional factor XI deficiency is a rare disorder. Acquired factor XI deficiency is extremely rare. The management of factor XI deficiency is not staightforward because of the unpredictable bleeding tendency that does not clearly relate to the factor XI level.

View Article and Find Full Text PDF
Article Synopsis
  • More people are taking a type of medicine called DOAC, and sometimes they need immediate help if they bleed a lot or need surgery.
  • There are special medicines called antidotes like idarucizumab for dabigatran and andexanet alfa for other DOACs to stop the effects quickly.
  • It's important to measure how much DOAC is in a person's blood to know if they need these antidotes, but sometimes the tests can be confusing after using the antidotes, so more research is needed on how to manage this well.
View Article and Find Full Text PDF

Investigation of the factors explaining individual differences in the acquisition of expert reading skills has become of particular interest these last decades. Non-verbal abilities, such as visual attention and executive functions play an important role in reading acquisition. Among those non-verbal factors, error-monitoring, which allows one to detect one's own errors and to avoid repeating them in the future, has been reported to be impaired in dyslexic readers.

View Article and Find Full Text PDF

The biodiversity impacts of agricultural deforestation vary widely across regions. Previous efforts to explain this variation have focused exclusively on the landscape features and management regimes of agricultural systems, neglecting the potentially critical role of ecological filtering in shaping deforestation tolerance of extant species assemblages at large geographical scales via selection for functional traits. Here we provide a large-scale test of this role using a global database of species abundance ratios between matched agricultural and native forest sites that comprises 71 avian assemblages reported in 44 primary studies, and a companion database of 10 functional traits for all 2,647 species involved.

View Article and Find Full Text PDF
Article Synopsis
  • Organ transplantation improves life expectancy and quality for patients with severe organ failure, with donors often coming from brain death cases.
  • Due to organ shortages, criteria for donor selection are expanding to include donors after circulatory death, though this raises concerns about the quality of the organs.
  • The review highlights ischemia-reperfusion injury as a key issue during transplants, exploring how thrombo-inflammation and coagulation impact this injury, while assessing anticoagulant therapies for better outcomes.
View Article and Find Full Text PDF

Point-of-care testing (POCT) for D-dimer is an alternative to -laboratory testing for the exclusion of venous thromboembolism (VTE). This critical review by the "CEC et biologie délocalisée" working group of the "Société Française de Thrombose et d'Hémostase" (French Society of -Thrombosis and Haemostasis) aims to present the characteristics of six POCT D-dimer assays available in France in 2023. The article highlights the need to define VTE -exclusion thresholds specific to each technique and validated by clinical studies.

View Article and Find Full Text PDF

Background: Additional histologic features of T3 colon cancer, such as tumour depth invasion beyond muscularis propria and elastic lamina invasion (ELI), have taken interest for a more accurate staging.

Methods: Patients with pT3 and pT4a (control group) colon adenocarcinoma were retrospectively collected from our institutional database. The study group was divided according to depth of tumour invasion < 5 mm and ≥ 5 mm, and into ELI - and ELI + .

View Article and Find Full Text PDF
Article Synopsis
  • Renal ischaemia reperfusion (I/R) leads to oxidative stress, inflammation, and organ failure, with macrophages playing a key role in clearing cell debris through the receptor MerTK.
  • This study compared natural MerTK mutant rats (RCS) and wild type rats (WT) to understand MerTK’s impact on kidney damage following I/R induced by clamping renal arteries.
  • Findings from various analyses suggest that exploring MerTK's role could enhance our understanding of kidney injury and recovery processes in renal I/R models.
View Article and Find Full Text PDF

This study aims at identifying the tools necessary for COVID-19 health emergency management, with particular reference to the period following the first lockdown, a crucial phase in which it was important to favor the maintenance of protective behaviors. It also aims at identifying the messages and sources that were most effective in managing communication correctly in such a crucial phase that is likely characterized by a fall in perceived health risk (due to the flattening of the epidemic curve) and a simultaneous rise in perceived economic and social risks (due to the enduring calamity). Knowing what source will be most effective to convey a specific message is fundamental in enabling individuals to focus on and comply with the rules.

View Article and Find Full Text PDF

Land-use change is a root cause of the extinction crisis, but links between habitat change and biodiversity loss are not fully understood. While there is evidence that habitat loss is an important extinction driver, the relevance of habitat fragmentation remains debated. Moreover, while time delays of biodiversity responses to habitat transformation are well-documented, time-delayed effects have been ignored in the habitat loss versus fragmentation debate.

View Article and Find Full Text PDF

Pancreatic solid pseudopapillary neoplasm (pSPN) is a rare exocrine neoplasm, which generally occurs in young women. This study analyses the clinical characteristics of pSPN in male patients through a systematic review of the literature, adding three new cases from our institution. We reviewed our experience in Pspns, and we performed a systematic review of pSPN of all articles published in English in PubMed and SCOPUS from 1980.

View Article and Find Full Text PDF
Article Synopsis
  • Pregnancy and postpartum present significant bleeding risks for haemophilia carriers and their newborns.
  • A study involving 104 carriers and 119 newborns in France over five years found 30% experienced bleeding events, mostly after delivery.
  • Factors such as cesarean sections and low factor levels increased bleeding risk, highlighting the need for specialized care in these situations.
View Article and Find Full Text PDF

Background:  Heparin-induced thrombocytopenia (HIT) is a rare complication of heparin treatments, and only a few large patient cohorts have been reported. In this study, biological and clinical data from 144 French patients with HIT were analyzed in comparison with the literature.

Methods:  The diagnosis of HIT was confirmed in all patients by an immunoassay combined with serotonin release assay.

View Article and Find Full Text PDF

Objective: Over the ongoing pandemic of coronavirus disease 2019 (COVID-19), the demand for critical care beds among medical services has rapidly exceeded its supply. Elective surgery has comprehensively been drastically limited and allocating intensive care beds to emergency cases or to high risk scheduled elective cases has become an even more difficult task. Here we present our experience which could help to handle undelayable surgical procedures during this emergency.

View Article and Find Full Text PDF

Understanding the trade-offs between biodiversity conservation and agricultural production has become a fundamental question in sustainability science. Substantial research has focused on how species' populations respond to agricultural intensification, with the goal to understand whether conservation policies that spatially separate agriculture and conservation or, alternatively, integrate the two are more beneficial. Spatial heterogeneity in both species abundance and agricultural productivity have been largely left out of this discussion, although these patterns are ubiquitous from local to global scales due to varying land capacity.

View Article and Find Full Text PDF

The previous research attempts to reduce the influence of the belief bias on deductive thinking have often been unsuccessful and, when they succeeded, they failed to replicate. In this paper, we propose a new way to see an old problem. Instead of considering the analytical abilities of the respondent, we focus on the communicative characteristics of the experimental task.

View Article and Find Full Text PDF

Background: Acute myocardial infarction is a leading cause of death worldwide. Though highly beneficial, reperfusion of myocardium is associated with reperfusion injury. While indirect inhibition of Factor Xa has been shown to attenuate myocardial ischemia-reperfusion (I/R) injury, the underlying mechanism remains unclear.

View Article and Find Full Text PDF

Purpose: This study aims to assess written word recognition in French-speaking children with severe developmental language disorder (DLD), using a task of reading in silence. The objective is to determine if the balance between the phonological reading route and the orthographic route of these children is similar to that of typically developing children, on the basis of the so-called "dual route" model.

Method: A visual lexical decision task was used in 19 children with severe DLD (average age: 11.

View Article and Find Full Text PDF

Pragmatics can be defined as the way in which language is used to communicate in a given social context. Although there is a lack of a standardized assessment, healthcare professionals find themselves confronted with pragmatic language skill impairments in children with neurodevelopmental disorders or brain injuries. The characterization of language use causes problems in social interactions, which has clinical implications in daily life.

View Article and Find Full Text PDF

Ischemia-reperfusion (I/R) injury is a leading cause of acute renal dysfunction. Remote ischemic conditioning (rIC) is known to protect organs exposed to I/R. We sought to investigate whether rIC would influence renal function recovery in a severe renal I/R injury rat model.

View Article and Find Full Text PDF

Introduction: Fondaparinux (FDX) was demonstrated to be cardioprotective in a rat model of myocardial ischemia reperfusion. In this model, FDX reduced infarct size after 2h of reperfusion, involving the activation of the survivor activating factor enhancement (SAFE) pathway as early as 30min post-reperfusion. Our aim was to study if this cardioprotection could be explained by anti-inflammatory mechanisms and a protective effect on vessels.

View Article and Find Full Text PDF