Publications by authors named "M.-E. Llamas"
Article Synopsis
- Bile acids play a crucial role in the gut by interacting with gut microbiota to regulate immune responses, although their exact physiological roles are not well understood.
- A new study identified two bile acid metabolites, 12-oxo-lithocholic acid (BAA485) and 11-oxo-12-hydroxylithocholic acid methyl ester (BAA473), which can activate the inflammasome, promoting the secretion of interleukin-18 (IL-18) in immune cells.
- The research suggests that these bile acid analogues may facilitate gut immune responses and could be important for understanding gut homeostasis and potential links to autoimmune diseases.
