Sleep spindle density and temporal clustering are associated with sleep-dependent memory consolidation in Parkinson's disease.

Study Objectives: Sleep is required for successful memory consolidation. Sleep spindles, bursts of oscillatory activity occurring during non-rapid eye movement sleep, are known to be crucial for this process and, recently, it has been proposed that the temporal organization of spindles into clusters might additionally play a role in memory consolidation. In Parkinson's disease, spindle activity is reduced, and this reduction has been found to be predictive of cognitive decline.

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Unlabelled: R. Mssrouri, S. Benamr, A.