Publications by authors named "M-F Tripodi"

Article Synopsis
  • The study looks at bradykinesia, which is when movement becomes slow and small, particularly in people with Parkinson's disease (pwPD) during a hand-tapping task.
  • Researchers compared 25 people with Parkinson's to 25 healthy controls using a brain scan and special gloves to measure their hand movements.
  • They found that people with Parkinson's had less movement and their brains showed different activity patterns, losing some coordination areas and using more cognitive areas instead, which helps understand how their movement problems happen.
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Introduction: Idiopathic venous thromboembolism (VTE) is associated with the risk of cancer but the risk factors for cancer development in such patients are still uncertain.

Aim: To assess risk factors for the development of cancer after a standard course of anticoagulation in patients with first episode of idiopathic VTE.

Materials And Methods: Subjects were enrolled in the three large prospective multicentre studies: PROLONG (NEJM 2006) PROLONG II (Blood 2010) and DULCIS (Blood 2014).

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Background: Endogenous ouabain (EO) has been linked with long-term changes in sodium balance and cardiovascular structure and function. The biosynthesis of EO involves, cholesterol side-chain cleavage (CYP11A1), 3-beta-hydroxysteroid dehydrogenase (HSD3B) with sequential metabolism of pregnenolone and progesterone. Furthermore, the renal excretion of cardiac glycosides is mediated by the organic anion transporter (SLCO4C1) at the basolateral membrane and the P-glycoprotein (PGP) (encoded by MDR1) at the apical membrane of the nephron.

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