Publications by authors named "M van den Nieuwboer"
Aim: To facilitate the delivery of appropriate care, the aim was to test if a tailored, multifaceted de-implementation strategy (RENEW) (1) would lead to less low-value nursing care and (2) was acceptable, implementable, cost effective and scalable in the home-based nursing care context.
Design: A mixed-methods design.
Methods: The RENEW strategy with components on education, persuasion, enablement, incentives and training was introduced in seven teams from two organisations in the Netherlands.
Article Synopsis
- Hematologic cancers are prevalent in both adults and children, but many patients still face poor outcomes, highlighting the need for new treatments.
- The Wiskott-Aldrich syndrome protein (WASp) plays a crucial role in actin assembly and is primarily found in blood cells; researchers have created a new small molecule, EG-011, that activates its autoinhibited state.
- Trials show that EG-011 effectively combats various blood cancers like lymphoma and leukemia both in isolated tests and in living models, showcasing its unique mechanism related to actin polymerization.
Article Synopsis
- * Researchers conducted an online survey from February to April 2022, receiving responses from 776 nursing professionals, revealing common low-value practices like daily full-body washes and reusing catheter bags.
- * Findings suggest that factors like physician advice, care plans, and client requests drive these practices; however, a higher education level and being over 40 were linked to less frequent use of low-value care.
Cancer cells make extensive use of the folate cycle to sustain increased anabolic metabolism. Multiple chemotherapeutic drugs interfere with the folate cycle, including methotrexate and 5-fluorouracil that are commonly applied for the treatment of leukemia and colorectal cancer (CRC), respectively. Despite high success rates, therapy-induced resistance causes relapse at later disease stages.
View Article and Find Full Text PDFObjective: To explore how a clinical leadership training programme contributes to successful implementation of integrated dementia care in local primary care networks.
Methods And Analysis: A qualitative design was used in local primary care networks in the Netherlands. Twenty-six primary care professionals, nurses (n=22), general practitioners (n=2) and occupational therapists (n=2) followed a 2-year practice-based educational programme including individual coaching and interactive group training.