Publications by authors named "M van Oevelen"
Background: Impaired cognition, poor health-related quality of life (HRQoL) and depressive symptoms are common in older patients with kidney failure. Understanding what influences HRQoL is important, as older patients regard HRQoL as a health priority. This study examines whether cognitive functioning is associated with HRQoL and whether depressive symptoms mediate this effect in older patients with kidney failure.
View Article and Find Full Text PDFPrognostic information is needed to balance benefits and risks of cancer treatment in older patients. Metabolomics-based scores were previously developed to predict 5- and 10-year mortality (MetaboHealth) and biological age (MetaboAge). This study aims to investigate the association of MetaboHealth and MetaboAge with 1-year mortality in older patients with solid tumors, and to study their predictive value for mortality in addition to established clinical predictors.
View Article and Find Full Text PDFRationale & Objective: Apathy reflects diminished motivation, goal-directed behavior, and emotions, as well as less engagement in social interactions. Apathy overlaps with depression and is associated with cognitive decline. In the older individuals with chronic kidney disease (CKD), both depression and cognitive impairments are common, but apathy symptoms have been underreported.
View Article and Find Full Text PDFArticle Synopsis
- Conservative care (CC) is an important treatment option for kidney failure, but choosing between CC and dialysis can be complicated and benefits from patient involvement in the decision-making process.
- A systematic review of 20 articles revealed three main themes: awareness of treatment choices, the support system during decision-making, and the motivation behind choosing CC such as maintaining quality of life and minimizing treatment burden.
- Overall, patients often felt satisfied with their choice of CC, highlighting the need for improved communication and patient-centered approaches in treatment decisions.
Background: Patients on haemodialysis (HD) generally experience poor health-related quality of life (HRQoL) and a broad range of physical and mental symptoms, but it is unknown whether this differs between younger and older patients. We aimed to describe the trajectories of HRQoL and symptom burden of patients <70 and ≥70 years old and to assess the impact of symptom burden on HRQoL.
Methods: In incident Dutch HD patients, HRQoL and symptoms were measured with the 12-item Short Form Health Survey and Dialysis Symptom Index.