Effects of photobiomodulation combined with rehabilitation exercise on pain, physical function, and radiographic changes in mild to moderate knee osteoarthritis: A randomized controlled trial protocol.

Background: Photobiomodulation, specifically high-energy photobiomodulation therapy (H-PBMT), is gaining recognition as a promising non-invasive intervention for managing knee osteoarthritis (KOA). While H-PBMT has demonstrated effectiveness in reducing pain and improving physical function, most evidence to date focuses on short-term symptomatic relief. The potential for H-PBMT to offer sustained benefits and modify the underlying progression of KOA remains insufficiently explored, warranting further investigation.

Plant and marine-derived natural products: sustainable pathways for future drug discovery and therapeutic development.

Plant- and marine-derived natural products are rich sources of bioactive compounds essential for drug discovery. These compounds contain complex mixtures of metabolites, which collectively contribute to their pharmacological properties. However, challenges arise in the isolation of individual bioactive compounds, owing to their intricate chemistry and low abundance in natural extracts.

Rigour of Development of European Society of Cardiology, American College of Cardiology and American Heart Association guidelines over a 12-year period (2013-2024): a systematic review of guidelines.

Introduction: The ESC and ACC/AHA regularly publish guidelines for the management of cardiovascular disease. By definition, a guideline should follow strict methodological criteria, and have a transparent, traceable and reproducible development process. We aimed to assess the overall strength of the recommendations and rigour of methodological development in ESC and ACC/AHA guidelines.

Co(II)-Based 2D Coordination Polymer Featuring Energy Storage and Detection of Aqueous Inorganic Anions.

Herein, we have synthesized a Co(II)-based 2D coordination polymer [Co(5-AIA)(Imidazole)] () (AIA = 5-aminoisophthalic acid) via a solvothermal approach. SCXRD (single-crystal X-ray diffraction) was utilized to analyze the crystal structure of fabricated . Moreover, PXRD, TGA, FTIR, and SEM analyses were done to identify the structural features of fabricated .

Reversible Sol-Gel Transitions Mediated Organics Selective Uptake and Release for Simultaneous Water Purification and Chemicals Recovery.

The separation and recovery of useful organics from wastewater have been a promising alternative to tackling water pollution and resource shortages, while strategies that truly work have rarely been explored. Herein, a reversible CO triggered sol-gel state transformation mediated selective organics uptake-release system using a surface modified carbonitride (S-CN) is proposed and exhibits remarkable organics recovery performance from wastewater. Results show that CO can serve as a cross-linker for linking S-CN particles to form a hydrogel by electrostatic interaction and hydrogen bonding, which can be recycled to the pristine sol state simply by removing the cross-linked CO with Ar purging.