Muscle loss in cancer cachexia: what is the basis for nutritional support?

Cancer cachexia (CC) is characterized by significant skeletal muscle wasting, and contributes to diminished quality of life, while being associated with poorer response to treatment and with reduced survival. Chronic inflammation plays a central role in driving CC progression, within a complex interplay favoring catabolism. Although cachexia cannot be fully reversed by conventional nutritional support, nutritional intervention shows promise for the prevention and treatment of the syndrome.

Resveratrol Upregulates Antioxidant Factors Expression and Downmodulates Interferon-Inducible Antiviral Factors in Aging.

Immunosenescence, a process with a dysfunctional immune response that may favor infection is associated with an increase in inflammatory responses mediated by proinflammatory cytokines, characteristic of inflammaging. Aging and immunosenescence have a relationship relating to oxidative stress and inflammaging. Therefore, natural antioxidant compounds could be candidates for the control of the oxidative process.

Child Health Handbook in Primary Care: perspectives of family health professionals and mothers.

Objective: To understand the use of the Child Health Handbook in Primary Care from the perspective of family health professionals and mothers.

Method: Qualitative research, grounded in Symbolic Interactionism, with 25 family health professionals and 11 mothers, in a city in Northeast Brazil. The data were collected in the months of September and October 2020, through semi-structured interviews and submitted to inductive thematic analysis.

Mechanisms of action of bioprotective plant extracts against the ochratoxigenic Penicillium nordicum in dry-cured sausages.

Plant extracts are promising strategies to minimise the hazard associated with ochratoxin A (OTA) in dry-cured sausages. Nonetheless, their mechanisms have not been elucidated yet. The mechanisms by which rosemary (REO), thyme (TEO) and oregano (OEO) essential oils and the extract of acorn shell (AE) impact on the OTA production by Penicillium nordicum were evaluated.

SKIN COLOR DIFFERENCES AND HEALTH-RELATED QUALITY OF LIFE PERCEPTION AFTER GASTRIC BYPASS ROUX-EN-Y: A CROSS-SECTIONAL STUDY.

Background: Differences in skin color have socioeconomic and health implications; however, gaps persist in understanding health-related quality of life (HRQoL) perception.

Aims: To examine whether skin color differences influence HRQoL in obese patients undergoing Roux-en-Y gastric bypass surgery.

Methods: Cross-sectional study with participants of both genders, aged 18 to 60, and three to six months postoperatively.