Publications by authors named "M Zolfo"

Article Synopsis
  • - The text discusses the importance of learning outcomes in education and how integrating "A-SMART" (Action-oriented, Specific, Measurable, Achievable, Relevant, Time-bound) outcomes with the backward design process can enhance curriculum planning.
  • - It introduces a three-stage approach for educators: define desired results, determine acceptable evidence of learning, and plan learning activities, highlighting the significance of starting with action verbs.
  • - By adopting this method, educators can create clearer, more effective learning outcomes that improve assessment practices and educational experiences while addressing potential challenges in the process.
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Article Synopsis
  • The study analyzes the oral microbiome of over 7,000 salivary samples from families with children diagnosed with autism spectrum disorders (ASD) to identify differences compared to neurotypical siblings.
  • Researchers found 108 species that differentiate ASD subjects from neurotypical counterparts, with specific connections to cognitive impairment measured by IQ.
  • The findings suggest potential links between the oral microbiome and neurodevelopmental factors related to ASD, while noting that lifestyle differences might also play a role.
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Viruses are an abundant and crucial component of the human microbiome, but accurately discovering them via metagenomics is still challenging. Currently, the available viral reference genomes poorly represent the diversity in microbiome samples, and expanding such a set of viral references is difficult. As a result, many viruses are still undetectable through metagenomics even when considering the power of metagenomic assembly and binning, as viruses lack universal markers.

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Article Synopsis
  • Scientists are studying how the tiny living things in our gut (gut microbiome) can affect cancer treatment, specifically with a method called immune checkpoint blockade (ICB).
  • They looked at 175 patients with a type of skin cancer called melanoma to see how changes in the gut microbiome relate to how well the treatment works over time.
  • They found that certain types of gut bacteria can help predict if patients will do better or worse with the treatment, and understanding these changes can help doctors improve therapies in the future.
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An operational research study was conducted in 2019 to assess the quality of data submitted by antimicrobial resistance (AMR) surveillance sites in the Bagmati Province of Nepal to the National Public Health Laboratory for Global Antimicrobial Resistance and Use Surveillance System (GLASS). Measures were implemented to enhance the quality of AMR surveillance by strengthening capacity, improving infrastructure, implementing data sharing guidelines, and supervision. The current study examined reports submitted by surveillance sites in the same province in 2022 to assess whether the data quality had improved since 2019.

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