Elaboration and evaluation of an intraoral controlled release delivering system.

In order to improve the administration of drugs for all pathology of the oral cavity, we have developed an intraoral controlled release delivering system, permitting to reach high enough local concentrations for desirable therapeutic effect with minimal side effects. We have formulated tablets of 200 mg intended to be fixed on a tooth. These tablets resist food and drink attacks.

[Development and evaluation of an active substance controlled-release device for use in the oral cavity].

In order to improve drug administration for diseases of the oral cavity, we have developed an intraoral controlled release delivery system enabling local concentrations high enough for desirable therapeutic effect with minimal side effects. We have formulated 200 mg tablets to be fixed on a tooth. These tablets resist attacks by food and beverages.

Monitoring rural-urban drug trends: an analysis of drug arrest statistics 1976-1980.

Recent research on urban drug use indicates that the alarming upward trend identified during the late 1960s and early 1970s is stabilizing. However, there is disagreement concerning whether the same pattern holds for rural populations. Early research reported low rates of drug use in nonmetropolitan areas.

Drug arrest statistics: a proposal for their use.

The extent to which drug use has increased, decreased, or leveled in the recent past is still subject to debate. This inconclusiveness is at least partly the result of the researchers' inability to monitor drug use in a constant and ongoing fashion. Instead, cross-sectional studies of different populations taken at different points in time are most often used to examine "trends.