The effect of oral pancreatic enzymes on the intestinal flora of protein-deficient vervet monkeys challenged with Vibrio cholerae.

Jejunal bacterial flora in 11 protein deficient vervet monkeys (Cercopithecus aethiops) and four controls was studied. These were the same animals from an investigation previously reported in which it was shown that pancreatic extract modified the course of cholera infection in protein-deficient monkeys. The present study reports in addition that these animals the fluid in the upper jejunum contained significantly increased numbers of bacteria including Enterobacteriaceae compared to its predietary state and to that of the controls.

Effect of oral pancreatic enzymes on the course of cholera in protein-deficient vervet monkeys.

The effect of pancreatic extract on the course of cholera infection in protein-deficient vervet monkeys (Cercopithecus aethiops) was studied. Eleven animals were made protein deficient by diet. Thier intestinal pancreatic enzyme concentration decreased as they became protein depleted.