Publications by authors named "M Zeki Durak"

The aim of this study was to obtain data on Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) profiles of () isolates resulting from acquired immune memory in addition to their technological starter properties for the selection of potential starter cultures from local yogurt samples. A total of 24 isolates were collected from six local yogurt samples including Afyon/Dinar, Uşak, Konya/Karapınar, and Tokat provinces of Türkiye. Strain-specific CRISPR I-II-III and IV primers were used to determine the CRISPR profiles of the isolates.

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Background: To compare the long-term safety and efficacy of Adalimumab (ADA) and Infliximab (IFX) agents in biologic-naive patients with Ulcerative colitis (UC).

Methods: The key focus was on specific outcomes such as the requirement of hospitalization due to UC, colectomy, steroid administration, and severe infections that led to the discontinuation of therapy.

Results: Anti-TNF treatment was initiated in 208 of the 475 patients with ulcerative colitis.

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Article Synopsis
  • The study examines the best timing for endoscopy in elderly patients (65+) experiencing nonvariceal upper gastrointestinal bleeding (NVUGIB) and its effect on clinical outcomes.
  • Very early endoscopy (within 12 hours) showed significantly lower 30-day mortality rates and reduced need for surgical interventions compared to late endoscopy (after 24 hours).
  • Patients who had late endoscopy were more likely to experience rebleeding, indicating timing is crucial for improving patient outcomes in this demographic.
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