Publications by authors named "M Zarkovic"
Thyroglobulin (Tg) is a reliable marker for detecting recurrence in differentiated thyroid cancer (DTC) patients, but frequently occurring Tg antibodies (TgAbs) can hinder accurate measurement. We aimed to develop a preanalytical protocol for precise Tg detection in TgAb presence using the immunoradiometric assay (IRMA) platform. This study involved forty-five patients who underwent IRMA Tg and radioimmunoassay (RIA) TgAb measurements, including two patients monitored for recurrence and one with confirmed recurrence.
View Article and Find Full Text PDFThe thyroid gland has an important influence on the heart. Long-term exposure to high levels of thyroid hormones may lead to cardiac hypertrophy and dysfunction. The aim of the study was to evaluate the morphological and functional changes in the left ventricle in patients with hyperthyroidism caused by Graves' disease (GD) in comparison with healthy individuals, as well as to investigate potential differences in these parameters in GD patients in relation to the presence of orbitopathy.
View Article and Find Full Text PDFArticle Synopsis
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Glucose and Lipid Metabolism Disorders in Adults with Spinal Muscular Atrophy Type 3.
Diagnostics (Basel)
September 2024
Article Synopsis
- Spinal muscular atrophy type 3 (SMA3) is a genetic disease mainly affecting motor neurons, but recent findings show metabolic issues like fatty acid and glucose metabolism irregularities in patients.
- A study involving 23 adult SMA3 patients revealed that over 60% had lipid abnormalities, and a staggering 91.3% showed signs of insulin resistance, though none had full-blown diabetes.
- The results indicate a significant connection between muscle, liver, and fat tissue functioning in SMA3 patients, emphasizing the need for focused metabolic care to manage potential health risks as these individuals age.
Parental smoking and respiratory outcomes in young childhood cancer survivors.
Pediatr Blood Cancer
November 2024
Article Synopsis
- The study investigates the prevalence of parental smoking among childhood cancer survivors (CCS) in Switzerland and its impact on their respiratory health.* -
- Researchers found that 18% of mothers and 23% of fathers smoke; maternal smoking increased the likelihood of CCS experiencing recurrent upper respiratory infections and lower respiratory symptoms.* -
- The findings suggest that healthcare providers should focus on reducing caregiver smoking and offer support for smoking cessation to improve respiratory outcomes for CCS.*