Publications by authors named "M Zardini"
Background: Multicenter ventricular tachycardia (VT) ablation studies have shown poorer outcomes compared with single-center experiences. This difference could be related to heterogeneous mapping and ablation strategies.
Objectives: This study evaluated a homogenous simplified catheter ablation strategy for different substrates and compared the results with those of a single referral center.
Aims: We investigated quantitative expression, mutual aggregation and relation with hyperglycemia of insulin resistance (IR) and beta-cell dysfunction (BCD) in newly diagnosed type 2 diabetes.
Methods: We assessed IR with euglycemic hyperinsulinemic clamp and BCD with modelled glucose/C-peptide response to oral glucose in 729 mostly drug-naïve patients. We measured glycated hemoglobin, pre-prandial, post-prandial and meal-related excursion of blood glucose.
Article Synopsis
- A study investigated the rates and outcomes of cardiac implantable electronic device (CIED) procedures in patients with active COVID-19, using data from 53 medical centers across 13 countries.
- The CIED implantation rate among hospitalized COVID-19 patients ranged from 0 to 16.2 per 1000, with a notable 30-day complication rate of 13.9% and a 180-day mortality rate of 9.6%.
- Significant differences in patient outcomes were identified between Europe and North America, highlighting the need for careful consideration of risks when performing CIED procedures on patients with COVID-19.
Background: Undiagnosed sinus or atrioventricular node dysfunction may bias estimation of the real efficacy of cardiac pacing in preventing vasovagal reflex syncope. We assessed this hypothesis in the BIOSync CLS trial which showed that dual-chamber pacing with closed loop stimulation (CLS) remarkably reduced recurrences of syncope.
Methods And Results: In the study patients aged 40 years or older with ≥2 episodes of loss of consciousness in the last year and an asystolic response to Tilt-Table test were randomized to pacing ON (DDD-CLS mode) or pacing OFF (ODO mode).