Publications by authors named "M Zakkar"
Article Synopsis
- Vein graft disease refers to the inflammation and atherosclerosis that affects saphenous vein grafts used in coronary artery bypass surgery over time.
- The study employed a novel spatial transcriptomic analysis to explore how arterial blood flow affects gene expression in the long saphenous vein, identifying 413 significant genes that respond to haemodynamic changes.
- Findings revealed key pathways related to inflammation and tissue remodeling that could serve as potential therapeutic targets to prevent vein graft disease in the future.
Article Synopsis
- - The study evaluated the Arabic version of the EQ-5D tool for measuring health-related quality of life in atrial fibrillation patients in Syria, addressing a gap in existing data.
- - Involving 432 participants, the research demonstrated strong reliability and validity of the EQ-5D through various testing methods, confirming its effectiveness for this patient group.
- - The successful validation of the EQ-5D in this context encourages its broader use across Arabic-speaking regions, potentially enhancing healthcare decision-making and patient care strategies.
Purpose: In Northwest Territories (NWT), Canada, infection rates for chlamydia, gonorrhea, and syphilis are three to ten times higher than the national averages and have been steadily increasing. However, data are scarce on the socioeconomic, psychological, and behavioural factors associated with the proliferation of sexually transmitted infections (STIs) in NWT. To this extent, this study explores Indigenous mothers' perspectives on sexual health, STI risk factors and healthcare-seeking behaviours in NWT.
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- * Key predictors for CHF readmission included older age (≥60 years), diabetes mellitus, valvular heart disease, and hypertension, highlighting the need for careful management of these factors.
- * The findings suggest that integrated care addressing lifestyle and comorbidities is crucial for improving health outcomes in resource-limited settings, especially among AF patients.
: Grafting of LIMA to LAD has long been considered the gold-standard conduit choice for patients undergoing CABG. Despite this, the LSV remains the most used conduit by volume and some patients may not receive even a single arterial conduit. However, the outcomes in this group are not frequently explored.
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