Safety and Efficacy of Ferric Carboxymaltose for Iron Deficiency Anemia in Inflammatory Bowel Disease: A Systematic Review.

Ulcerative colitis and Crohn's disease, two types of inflammatory bowel disease (IBD), often cause anemia, primarily due to iron deficiency and chronic inflammation. Anemia negatively affects patients' daily functioning and quality of life, causing symptoms including headaches, exhaustion, and dyspnea. In IBD, iron deficiency arises from reduced intake, chronic blood loss, and impaired absorption.

Synthesis, crystal structure and Hirshfeld surface analysis of 2-{4-[(2-chloro-phen-yl)meth-yl]-3-methyl-6-oxopyridazin-1-yl}--phenyl-acetamide.

In the title mol-ecule, CHClNO, the 2-chloro-phenyl group is disordered to a small extent [occupancies 0.875 (2)/0.125 (2)].

Gut Microbiome and Its Role in Parkinson's Disease.

Parkinson's disease (PD) afflicted more than 8.5 million people globally in 2019, as the prevalence of the condition more than doubled during the preceding 25 years. Both non-motor symptoms, such as mood disorders and cognitive impairment, and motor symptoms, such as tremors and rigidity, are indicative of this progressive neurodegenerative disease.

Recurrent Gastrointestinal Symptoms and Diagnosis of Superior Mesenteric Artery Syndrome.

This is a case of a young lady who was admitted multiple times with complaints of inability to digest food and abdominal pain. She had nausea and vomiting for long periods and was unable to tolerate orally. As she was unable to tolerate oral feeding and losing weight, she was started on nasogastric feed (NG feed) and later percutaneous endoscopic gastrostomy (PEG) tube feeding because NG feed was uncomfortable for the patient and did not alleviate the problem.

Vitamin E and Non-alcoholic Fatty Liver Disease: Investigating the Evidence Through a Systematic Review.

Nonalcoholic fatty liver disease (NAFLD), now recognized as metabolic dysfunction-associated steatotic liver disease (MASLD), is a common chronic liver condition characterized by hepatic steatosis and inflammation, with an increased risk of developing fibrosis and cirrhosis. This systematic review aims to evaluate the effects of vitamin E supplementation on liver enzymes and histological features in patients with NAFLD/MASLD. We conducted a comprehensive literature search from July 14, 2024, to July 30, 2024, across multiple databases, including PubMed, MEDLINE, ScienceDirect, Europe PMC, the Cochrane Central Register of Controlled Trials (CENTRAL), ClinicalTrials.