Publications by authors named "M Yi"
Many virus species, including Ebola virus, Marburg virus, SARS-CoV-2, dengue virus (DENV) and Zika virus (ZIKV), exploit CD209 and CD209L as alternative or attachment receptors for viral cis- or trans-infection. Thus, CD209 and CD209L may be critical targets for the development of therapeutic monoclonal blocking antibody drugs to disrupt the infection process caused by multiple viruses. Here, we produced a human chimeric monoclonal blocking antibody that simultaneously blocks CD209 and CD209L, namely 7-H7-B1.
View Article and Find Full Text PDFThe risk factors and prediction model for postoperative pneumonia after craniotomy.
Front Cell Infect Microbiol
January 2025
Background: Craniotomy is highly susceptible to postoperative pneumonia, which significantly impacts the outcomes of patients undergoing such procedures. Our study aims to examine the risk factors associated with postoperative pneumonia and establish a predictive model with a nomogram to assess this risk.
Methods: We conducted a matched 1:1 case-control study involving 831 adult patients undergoing craniotomy at our hospital.
Exosomes derived from fibroblasts in DFUs delay wound healing by delivering miR-93-5p to target macrophage ATG16L1.
Biochim Biophys Acta Mol Basis Dis
January 2025
Diabetes is an extremely costly disease, one-third of which are attributed to the management of diabetic foot disease including chronic, non-healing, diabetic foot ulcers (DFUs). Therefore, much effort is needed to understand the pathogenesis of DFUs and novel therapeutics. We utilized exosome staining to confirm the interaction between fibroblast-derived exosomes and macrophages.
View Article and Find Full Text PDFArticle Synopsis
- This study examines the prevalence of co-infections with Burkholderia cepacia complex (Bcc) in patients with respiratory infections like COVID-19 and H7N9, highlighting a lack of previous research on this topic.
- A total of 49 Bcc isolates were analyzed from patients, revealing that those infected with COVID-19 had a higher rate of multidrug resistance and a shorter median lethal time compared to those with H7N9.
- The findings suggest that COVID-19-Bcc may have evolved from H7N9-Bcc, demonstrating increased virulence and antibiotic resistance in the context of respiratory infections.
Background: Uncertainty in illness is regarded as a source of stress, and tends to have adverse consequences on quality of life among older adults with chronic heart failure (CHF).
Objective: The purpose of this study was to identify distinct subgroups in uncertainty in illness, and to explore associated factors within the population of older adults with CHF.
Methods: We conducted a cross-sectional study using convenience sampling to survey 311 hospitalized older adults with CHF.