Publications by authors named "M Yen"

Marburg virus (MARV) disease (MVD) is an uncommon yet serious viral hemorrhagic fever that impacts humans and non-human primates. In humans, infection by the MARV is marked by rapid onset, high transmissibility, and elevated mortality rates, presenting considerable obstacles to the development of vaccines and treatments. Bats, particularly , are suspected to be natural hosts of MARV.

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Patients with hypoxemia require high-concentration oxygen therapy. However, prolonged exposure to oxygen concentrations 21% higher than physiological concentrations (hyperoxia) may cause oxidative cellular damage. Pulmonary alveolar epithelial cells are major targets for hyperoxia-induced oxidative stress.

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Article Synopsis
  • - This study investigates how different ways of measuring obesity affect mortality risk for patients on hemodialysis (HD), revealing conflicting findings across methods.
  • - A systematic review analyzed data from 23 studies, finding that while body mass index (BMI) indicated a lower mortality risk for obese HD patients, other methods like waist circumference showed an increased risk.
  • - The research highlights an "obesity paradox" in HD patients where higher BMI correlates with lower risk, suggesting that BMI may not effectively distinguish between fat and muscle mass, calling for further studies on obesity measurement techniques.
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Drug metabolite identification is an essential characterization process spanning multiple phases of drug discovery and development. Various data processing techniques have been employed in metabolite identification using high-resolution mass spectrometry. However, metabolite identification is not consistent among approaches.

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