Publications by authors named "M Yazid"
Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) can be isolated from umbilical cords which is abundant and easy to obtain. Due to their potent immunosuppressive properties, multilineage differentiation potential, and lack of ethical issues, WJ-MSCs are considered a promising candidate for therapeutic applications. However, large-scale in vitro expansion is necessary to obtain enough cells for therapeutic purposes.
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- Phoenixin (PNX) is a neuropeptide that significantly influences metabolism and reproduction, playing a role in energy homeostasis, glucose, lipid metabolism, and mitochondrial function.
- PNX is primarily found in the hypothalamus and is involved in reproductive hormone regulation, as well as being present in other tissues like the heart and pancreas, indicating its widespread metabolic control.
- The peptide acts through G protein-coupled receptor 173 (GPR173) and may have therapeutic potential for managing conditions like obesity, type 2 diabetes, and infertility, making further research crucial for developing treatment strategies.
Coronary artery bypass grafting (CABG) utilizing saphenous vein grafts (SVGs) stands as a fundamental approach to surgically treating coronary artery disease. However, the long-term success of CABG is often compromised by the development of intimal hyperplasia (IH) and subsequent graft failure. Understanding the mechanisms underlying this pathophysiology is crucial for improving graft patency and patient outcomes.
View Article and Find Full Text PDFTraumatic damage to the spinal cord (SCI) frequently leads to irreversible neurological deficits, which may be related to apoptotic neurodegeneration in nerve tissue. The MLC901 treatment possesses neuroprotective and neuroregenerative activity. This study aimed to explore the regenerative potential of MLC901 and the molecular mechanisms promoting neurogenesis and functional recovery after SCI in rats.
View Article and Find Full Text PDFBackground: Understanding human stem cell differentiation into osteoblasts and osteoclasts is crucial for bone regeneration and disease modeling. Numerous morphological techniques have been employed to assess this differentiation, but a comprehensive review of their application and effectiveness is lacking.
Methods: Guided by the PRISMA framework, we conducted a rigorous search through the PubMed, Web of Science and Scopus databases, analyzing 254 articles.