Publications by authors named "M Yakubu"
Objectives: The burgeoning prevalence of cardiometabolic disorders, including type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) within Africa is concerning. Machine learning (ML) techniques offer a unique opportunity to leverage data-driven insights and construct predictive models for MetS risk, thereby enhancing the implementation of personalised prevention strategies. In this work, we employed ML techniques to develop predictive models for pre-MetS and MetS among diabetic patients.
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- Dyslipidaemia is a major contributor to coronary artery disease (CAD) and cardiovascular issues globally, and understanding statin benefits is essential for its effective management.
- A web-based survey involving 313 physicians in Nigeria revealed that while most recognize elevated LDL-C as a key cause of CAD, many have concerns about statin side effects and their impact on patient adherence.
- The findings indicate significant knowledge and practice gaps in dyslipidaemia management among Nigerian physicians, suggesting a need for improvement initiatives to reduce cardiovascular risk.
Article Synopsis
- Anthonotha macrophylla is a plant known for its various ethnomedicinal uses, including treating venereal diseases, intestinal discomfort, and enhancing sexual behavior, especially noted for scientific validation in female rats but lacking studies in male rat models with sexual dysfunction.* -
- The study aimed to explore the aphrodisiac effects of an aqueous extract from Anthonotha macrophylla leaves in male rats experiencing paroxetine-induced sexual dysfunction.* -
- Results indicated that the extract was rich in minerals and amino acids, and paroxetine negatively impacted sexual behavior, suggesting the need for further analysis on the extract’s potential benefits for male sexual health.*
Article Synopsis
- - Rollet's Mixed Chancre is a rare clinical presentation of sexually transmitted infections (STIs) where two STIs occur simultaneously at the same infection site.
- - A case study involved a 32-year-old Brazilian woman who had a swollen lymph node and an ulcerated lesion in her inguinal region, which developed over 10 days.
- - The patient was successfully treated with antibiotics, underscoring the need for awareness of uncommon STI manifestations and the importance of thorough STI screening and treatment adherence.
Objective: Rhizome (CLR), due to its potent antioxidant phytochemical constituents, was investigated for its effects on bisphenol A (BPA)-induced cardiovascular and renal damage.
Materials And Methods: Sixty rats were randomly selected, and grouped as control, BPA (100 mg/ kg), BPA and CLR 100 mg/kg, BPA and CLR 200 mg/kg, CLR 100 mg/kg, and CLR 200 mg/kg for 21 days. Oxidative stress indices, antioxidant status, blood pressure parameters, genotoxicity, and immunohistochemistry were determined.