Publications by authors named "M Yaegashi"
Article Synopsis
- In Japan, comprehensive genome profiling (CGP) as a diagnostic tool has been available through public insurance since June 2019, but only a small percentage of cancer patients are actually receiving treatments based on this data.
- A study analyzed 219 patients with various cancers from Iwate Medical University Hospital, finding that only 6.4% acted on drug recommendations made by the Molecular Tumor Board after CGP analysis.
- Despite low drug adoption rates, CGP proved useful for monitoring circulating tumor DNA (ctDNA), helping predict early relapses and evaluate treatment responses in a significant number of cases.
Article Synopsis
- Bladder injuries during laparoscopic surgery are uncommon but can be serious, especially in patients with urachal remnants, which increase the risk during suprapubic port insertion.
- A case of a 46-year-old man with cecal cancer experienced a bladder injury due to a urachal remnant during laparoscopic surgery, leading to a successful repair and uncomplicated recovery.
- The case highlights the challenges in diagnosing asymptomatic urachal remnants preoperatively and suggests that sagittal CT scans can help identify them, recommending careful port placement to prevent bladder injuries.
Purpose: Pre-existing hypertension is reportedly a major risk factor for bevacizumab-induced proteinuria. However, few studies have focused on the effects of blood pressure (BP) control on proteinuria during bevacizumab treatment. We report a retrospective study of the association between poor BP control and the risk of developing proteinuria in patients with colorectal cancer (CRC).
View Article and Find Full Text PDFIntroduction: Few cases of intestinal obstruction after colostomy are caused by internal hernia. Some institutions perform stomas through the extraperitoneal route because some patients experience an internal hernia outside the stoma performed through the intraperitoneal route.
Presentation Of Case: A 72-year-old woman presented with a history of laparoscopic abdominoperineal resection (APR).
Background: The prognostic value of the pathological response to preoperative chemoradiotherapy (CRT) in rectal cancer (RC) remains unknown.
Objectives: We aimed to assess the predictive value of the response to CRT that was derived from an evaluation of the histological findings (whole-section vs. representative-section sampling) and attempted to determine an objective cut-off value for the tumor regression grade (TRG).