Publications by authors named "M Ya Druzin"

Article Synopsis
  • Mental health conditions and epilepsy often occur together during pregnancy and are linked to higher rates of severe maternal morbidity (SMM).
  • A study examining over 5 million births in California found that SMM was notably higher in pregnant individuals with either or both conditions compared to those without.
  • Results showed that the odds of SMM increased significantly with mental health issues (2.13 times), epilepsy (3.79 times), and even more so for those with both conditions (4.91 times), stressing the importance of monitoring these risks in pregnant women.
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Article Synopsis
  • Scientists studied how short telomeres (the ends of DNA that protect our genes) in new moms relate to two pregnancy issues: preeclampsia (a condition that can happen during pregnancy) and early birth (spontaneous preterm birth).
  • They looked at groups of pregnant women from two different areas: one mostly had higher income and one was from a lower income area, to see if different backgrounds affected the results.
  • They found that moms with preeclampsia in the lower income group had shorter telomeres, but overall, there wasn't a clear link between short telomeres and early births in either group.
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Background: Recent studies have suggested that pregnancy accelerates biologic aging, yet little is known about how biomarkers of aging are affected by events during the peripartum period. Given that immune shifts are known to occur following surgery, we explored the relation between mode of delivery and postpartum maternal leukocyte telomere length (LTL), a marker of biologic aging.

Study Design: Postpartum maternal blood samples were obtained from a prospective cohort of term, singleton livebirths without hypertensive disorders or peripartum infections between 2012 and 2018.

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Objective: Patients with systemic lupus erythematosus (SLE) are at risk for pregnancy complications such as pre-eclampsia and eclampsia. These clinically important complications are associated with maternal morbidity, mortality, and postpartum cardiovascular disease. Some studies suggest that hydroxychloroquine (HCQ) may reduce pre-eclampsia risk in lupus pregnancy.

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