Publications by authors named "M YATES"
Cerebrospinal fluid (CSF) biomarkers are currently the only clinically validated biofluid diagnostic test for Alzheimer's Disease (AD) available in Australia. Testing of CSF biomarkers via lumbar puncture (LP), including quantification of amyloid-β peptide, total tau protein, and phosphorylated tau, can give insight into underlying pathophysiological changes and provide greater certainty in confirming or excluding the presence of Alzheimer's disease changes compared to standard clinical and radiological assessments. Despite CSF analysis being a safe and cost-effective diagnostic method, the use of CSF biomarkers in the evaluation of potential AD remains limited in Australian clinical practice due to a variety of factors, including regional access challenges, concerns over the perceived invasiveness of LP and a lack of confidence among clinicians in interpreting the results.
View Article and Find Full Text PDFBackground: Biotechnologies that utilize microorganisms as production hosts for lipid synthesis will enable an efficient and sustainable solution to produce lipids, decreasing reliance on traditional routes for production (either petrochemical or plant-derived) and supporting a circular bioeconomy. To realize this goal, continuous biomanufacturing processes must be developed to maximize productivity and minimize costs compared to traditional batch fermentation processes.
Results: Here, we utilized biofilms of the marine bacterium, Marinobacter atlanticus, to produce wax esters from succinate (i.
Article Synopsis
- Increasing numbers of women are pursuing itinerant lifestyles in Australia, challenging traditional views of women as they age and expanding their ambitions beyond conventional roles.
- The study involved interviews with 29 women who traveled alone or with other women, and focused on four narratives that illustrate key themes such as adventure, self-exploration, and life control.
- The stories highlight the richness and diversity of these women's experiences, showcasing their journeys toward personal growth, independence, and a redefinition of aging.
Article Synopsis
- * Over 16,000 patients were screened, revealing a high prevalence of CI (37.8%) and a significantly higher rate of hospital-acquired complications (HACs) in those with CI, but the intervention did not lead to a significant reduction in HAC rates.
- * The results showed variations in the program’s implementation across hospitals, and despite some slight overall reductions in HAC rates, these changes were not statistically significant, suggesting the need for further refinement in intervention strategies.
Objectives: This paper aimed to develop a model to describe help-seeking for dementia diagnosis. The practical model is intended to guide public health interventions to increase help-seeking.
Method: The model was developed by our multidisciplinary team based on qualitative semi-structured interviews in English ( = 33) and Chinese ( = 8) with older people, people with dementia and carers.