Publications by authors named "M Y van der Meulen"
Purpose: To evaluate the cost utility of a 9-month supervised exercise program for patients with metastatic breast cancer (mBC), compared with control (usual care, supplemented with general activity advice and an activity tracker). Evidence on the cost-effectiveness of exercise for patients with mBC is essential for implementation in clinical practice and is currently lacking.
Methods: A cost-utility analysis was performed alongside the multinational PREFERABLE-EFFECT randomized controlled trial, conducted in 8 centers across Europe and Australia.
Article Synopsis
- Chronic pain in older adults disrupts how they process sensory information, particularly affecting their attention and emotional responses to tactile stimulation.
- The study involved three groups: older adults with chronic pain, pain-free older adults, and younger adults, analyzing their brain responses to different types of stimuli in emotional contexts.
- Results showed that older adults with chronic pain had heightened brain activity in response to both frequent and deviant stimuli, indicating a reduced ability to ignore irrelevant sensory information, especially linked to emotional contexts.
Drug-resistant tuberculosis (TB) poses a significant public health concern in South Africa due to its complexity in diagnosis, treatment, and management. This study assessed the diagnostic performance of the Xpert MTB/XDR test for detecting drug resistance in patients with TB by using archived sputum sediments. This study analyzed 322 samples collected from patients diagnosed with TB between 2016 and 2019 across South Africa, previously characterized by phenotypic and genotypic methods.
View Article and Find Full Text PDFIncreasing research points to a decline in the ability to internally regulate pain as a contributing factor to the increased pain susceptibility in aging. This study investigated the connection between pain regulation and resting-state functional connectivity (rsFC) in older adults with chronic pain. We compared functional magnetic resonance imaging rsFC of 30 older adults with chronic pain (69.
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