High perioperative lactate levels as a potential predictor for severe acute kidney injury following aortic arch surgery.

Background: Acute type A aortic dissection (ATAAD) is a life-threatening condition that often requires total aortic arch replacement (TAR) combined with frozen elephant trunk (FET) implantation. Despite advancements in surgical techniques and preoperative management, postoperative acute kidney injury (AKI) remains a prevalent complication that significantly affects patient prognosis, particularly severe AKI. The aim of this study was to investigate the predictive value of perioperative lactate levels in severe postoperative AKI after TAR.

Dendrite-free Zn anode induced by Sn/NC towards highly efficient Zn-ion batteries.

Herein, Sn nanoparticles supported on N-doped carbon (Sn/NC) were constructed by a g-CN assisted strategy for the interface layer of Zn anodes in Zn-ion batteries. The presence of Sn/NC effectively regulates the zinc plating/stripping process, which makes Sn/NC@Zn outstanding in both symmetrical and full cells.

Synergistic activation of peroxydisulfate by photothermal and FeS-loaded air-laid cloth in a shallow continuous flow reactor.

Synergistic activation of persulfate by photothermal and solid catalysts is an effective method for degrading organic pollutants. However, the batch reaction mode not only fails to fully utilize photothermal, but also makes it hard to separate the solid catalysts from the reaction solution. In this work, a shallow continuous flow way of effluent was set up for synergistic activation of peroxydisulfate (PDS) by photothermal and FeS-loaded air-laid cloth (FeS-ALC).

Aptamer-Proximity Ligation Coupled with Rolling Circle Amplification Strategy for an Ultrasensitive Analysis of Tumor-Derived Extracellular Vesicles PD-L1.

Tumor-derived extracellular vesicles (T-EVs) PD-L1 are an important biomarker for predicting immunotherapy response and can help us understand the mechanism of resistance to immunotherapy. However, this is due to the interference from a large proportion of nontumor-derived EVs. It is still challenging to accurately analyze T-EVs PD-L1 in complex human fluids.

Correlation between lipoprotein-associated phospholipase A2 and diabetic peripheral neuropathy in patients with type 2 diabetes mellitus: A cross-sectional study.

Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an enzyme implicated in inflammation and oxidative stress, and has been associated with cardiovascular conditions and adverse outcomes, particularly in diabetes and its complications. However, no prior studies have examined the relationship between Lp-PLA2 and diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM). This research aims to explore the potential association between Lp-PLA2 and DPN.