Are there inequalities in ovarian cancer diagnosis and treatment in England? A population-based study.

Introduction: Ovarian cancer ranks as the sixth leading cause of cancer-related mortality among women. Notably, there is a deprivation gradient in survival rates, with individuals from more affluent socioeconomic groups more likely to be alive at five years following diagnosis. This study examines disparities in treatment received and the timeliness of diagnosis and treatment across different socioeconomic groups in England, a country with universal healthcare.

Handball playing volume and knee injury risk in youth handball: the influence of sex.

Objectives: To investigate if sex modifies the association between change in weekly handball volume and knee injury risk in youth handball players.

Design: Prospective cohort study.

Methods: 679 players aged 14-18 reported weekly on any new handball-related knee injury and handball volume (training and competition hours) over 31 weeks through the SMS, phone and medical examination system.

Can Baseline MRI Findings Identify Who Responds Better to Early Surgery Versus Exercise and Education in Young Patients With Meniscal Tears? A Subgroup Analysis From the DREAM Trial.

To investigate whether magnetic resonance imaging (MRI) findings modified the outcomes of early surgery compared to exercise and education in young patients with meniscal tears. A secondary effect modifier analysis of a randomized controlled trial. The primary outcome was change from baseline to 12 months in the mean score of 4 Knee injury and Osteoarthritis Outcome Score subscales (KOOS).

Elevated levels of PAI-1 precede the occurrence of type 2 diabetes mellitus.

Aims: Plasminogen activator inhibitor-1 (PAI-1) is the main inhibitor of the fibrinolytic system and is mainly secreted from adipose tissue. It is associated with cardiovascular disease and has also been considered a possible early risk marker for type 2 diabetes. Here, we present the results of a large prospective study investigating PAI-1 levels in relation to incident type 2 diabetes mellitus.

"Active Larynx": Preliminary Evaluation of the Reliability of Visual Assessments of Laryngeal Inflammation.

Objective: The term "active larynx" is a nonspecific and subjective term used by otolaryngologists to describe laryngeal inflammation that can influence the timing of airway reconstruction. We sought to measure the reliability of visual assessments of laryngeal inflammation for later scale development.

Study Design: A cross-sectional study.