Background: Mechanical thrombectomy (MT) is the standard of care for eligible acute ischemic stroke (AIS) patients with large vessel occlusion (LVO) since 2015.
Aim: Our aim was to determine the key challenges for MT implementation and access worldwide.
Methods: We conducted an international online survey consisting of 37 questions, distributed through the World Stroke Organization network, and as invited by co-authors between December 2022 and March 2023.
BMC Pregnancy Childbirth
October 2024
Operators of water distribution systems (WDSs) need continuous and timely information on pressures and flows to ensure smooth operation and respond quickly to unexpected events. While hydraulic models provide reasonable estimates of pressures and flows in WDSs, updating model predictions with real-time sensor data provides clearer insights into true system behavior and enables more effective real-time response. Despite the growing prevalence of distributed sensing within WDSs, standard hydraulic modeling software like EPANET do not support synchronous data assimilation.
View Article and Find Full Text PDFBackground: Carotid web (CaW)-related contrast stagnation on digital subtraction angiography (DSA) may be a marker supporting the pathophysiological theory of stasis and thrombosis/embolization. We aim to assess the correlation between DSA hemodynamic parameters with CT angiography (CTA) structural measurements and clinical characteristics.
Methods: Cross-sectional analysis of consecutive patients with CaW who underwent CTA+DSA.
Primary sclerosing cholangitis (PSC) is a rare, progressive disease, characterized by inflammation and fibrosis of the bile ducts, lacking reliable prognostic biomarkers for disease activity. Machine learning applied to broad proteomic profiling of sera allowed for the discovery of markers of disease presence, severity, and cirrhosis and the exploration of the involvement of CCL24, a chemokine with fibro-inflammatory activity. Sera from 30 healthy controls and 45 PSC patients were profiled with proximity extension assay, quantifying the expression of 2870 proteins, and used to train an elastic net model.
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