Distribution, Phytochemical Insights, and Cytotoxic Potential of the Genus: A Comprehensive Review of , , and .

This review evaluates the cytotoxic potential of the genus, with a focus on , , and . These species, known for their diverse phytochemical compositions, exhibit notable cytotoxic effects that suggest their utility in natural cancer treatments. Compounds such as quercetin, kaempferol, and sesbagrandiforian A and B have been highlighted for their strong antioxidant and antiproliferative effects, further emphasizing their therapeutic potential.

Functional Analysis of Durum Wheat GASA1 Protein as a Biotechnological Alternative Against Plant Fungal Pathogens and a Positive Regulator of Biotic Stress Defense.

Plants are frequently challenged by a variety of microorganisms. To protect themselves against harmful invaders, they have evolved highly effective defense mechanisms, including the synthesis of numerous types of antimicrobial peptides (AMPs). Snakins are such compounds, encoded by the (Gibberellic Acid-Stimulated Arabidopsis) gene family, and are involved in the response to biotic and abiotic stress.

Novel nano-sized N-Thiazolylpyridylamines targeting CDK2: Design, divergent synthesis, conformational studies, and multifaceted In silico analysis.

This study involves the design, divergent synthesis, conformational and structural analysis, target prediction, and molecular docking simulations of novel nano N-thiazolylpyridylamines 2-7 and 10 as potential cyclin-dependent kinase 2 (CDK2) inhibitors. Using a divergent synthesis approach, the compounds were designed with structural variation and optimization in mind. The conformational and structural properties were explored through various spectroscopic techniques, confirming the structure, stability, and preferred conformations.

Molecular docking and / studies of a novel thiadiazole Schiff base as a hepatoprotective drug against angiogenesis induced by breast cancer.

Two new thiadiazole imidazolium salicylidene Schiff bases (TISSBs) were successfully synthesized, and their structures were analyzed comprehensively using spectroscopic techniques. The results of the MTT assay showed that TISSB2 was the safest and most effective anti-breast cancer agent. The anti-angiogenic activity of TISSB2 was evaluated using tests in Ehrlich ascites carcinoma (EAC)-bearing Swiss albino mice.

Improved hydrogen production performance of an S-scheme NbO/LaO photocatalyst.

Addressing the intricate challenge of simultaneously improving the separation of photoinduced electron-hole pairs and enhancing redox potentials to produce hydrogen fuel demands the rational design of S-scheme heterojunction photocatalysts. Herein, we used a hydrothermal process to integrate NbO nanorods and LaO nanosheets to design an NbO/LaO S-scheme system for photocatalytic hydrogen production under simulated sunlight illumination. Notably, the optimal hydrogen production performance of NbO/LaO (the molar ratio of NbO to LaO is 0.