Unlabelled: The domestication of cattle provided Propionibacteriaceae the opportunity to adapt to human skin. These bacteria constitute a distinct genus ( ), and a single species within that genus ( ) dominates 25% of human skin. protects humans from pathogen colonization, but it can also infect indwelling medical devices inserted through human skin.
View Article and Find Full Text PDFUnlabelled: Adhesion to and clearance of the mesothelial monolayer are key early events in metastatic seeding of ovarian cancer. ROR2 is a receptor tyrosine kinase that interacts with Wnt5a ligand to activate noncanonical Wnt signaling and has been previously shown to be upregulated in ovarian cancer tissue. However, no prior study has evaluated the mechanistic role of ROR2 in ovarian cancer.
View Article and Find Full Text PDFNeuropsychiatric and neurodegenerative disorders are correlated with cellular stress. Macroautophagy (autophagy) may represent an important protective pathway to maintain cellular homeostasis and functionality, as it targets cytoplasmic components to lysosomes for degradation and recycling. Given recent evidence that some novel psychiatric treatments, such as the neuroactive steroid (NAS) allopregnanolone (AlloP, brexanolone), may induce autophagy, we stably transfected human embryonic kidney 293 (HEK) cells with a ratiometric fluorescent probe to assay NAS effects on autophagy.
View Article and Find Full Text PDFBehav Res Methods
August 2024
To detect bots in online survey data, there is a wealth of literature on statistical detection using only responses to Likert-type items. There are two traditions in the literature. One tradition requires labeled data, forgoing strong model assumptions.
View Article and Find Full Text PDFWhile trying to infer laws of behavior, accounting for both within-subjects and between-subjects variance is often overlooked. It has been advocated recently to use multilevel modeling to analyze matching behavior. Using multilevel modeling within behavior analysis has its own challenges though.
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