Influence of olfactory bulbectomy and the serotonergic system upon intermale aggression and maternal behavior in the mouse.

Biochemical parameters in the brains of olfactory bulbectomized male and female mice were studied in two experiments, followed by three experiments in which 5-HTP was injected into bulbectomized males and females to try to block abnormal behaviors. In Experiment 1 bulbectomized male and female mice had significantly less tryptophan hydroxylase in their brains than did sham controls. Neither 5-hydroxtryptophan decarboxylase nor tyrosine hydroxylase activity was affected.

Handling rabbits in infancy: in search of a critical period.

In Experiment 1 rabbits were handled for the first 10 days of life while controls were not disturbed. In Experiment 2 rabbits were handled on Days 11-20. In Experiment 3 rabbits were handled on Days 1-10, 11-20, 1-20, or were not handled.