Publications by authors named "M Wottke"

Aims: We sought to determine the long-term outcome of high-risk patients who underwent transcatheter aortic valve replacement (TAVR) with first-generation devices with a focus on the identification of predictors for mortality and valve durability.

Methods And Results: Consecutive patients in our prospective single-centre registry undergoing TAVR with first-generation devices (n=214 CoreValve; n=86 SAPIEN) between 06/2007 and 07/2009 were retrospectively analysed (n=300, mean age 81.43±6.

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Introduction And Objectives: TAVR is thought to change the volumes, characteristics, and outcomes of patients with aortic stenosis undergoing SAVR. We sought to investigate the impact of increasing transcatheter aortic valve replacement (TAVR) volumes on surgical aortic valve replacement (SAVR) volumes and to assess the evolution in baseline demographics and its impact on 30-day clinical outcomes across TAVR and SAVR patients.

Methods: From June 2007 through September 2015, 3543 consecutive patients with severe aortic stenosis who underwent TAVR (n=1407) or SAVR (n=2136) in a single center were subcategorized into nine cohorts defined by procedure year.

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Article Synopsis
  • The study aimed to assess existing risk models for predicting mortality in adult patients undergoing congenital heart surgery and to evaluate a new model called the GUCH score specifically designed for this demographic.
  • Researchers analyzed data from 830 surgeries performed between 2004 and 2013, comparing various risk scores such as ABC, ACC, RACHS-1, and STS-EACTS.
  • Results showed that the GUCH score was the most effective at predicting mortality as it combines factors from existing models with a focus on comorbidities and patient age, indicating the importance of these factors in mortality predictions.
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Article Synopsis
  • The St Jude Medical Trifecta valve is a new type of heart valve for replacing the aortic valve, aimed at improving surgical outcomes for patients with severe valve issues.
  • A study involving 837 patients who received the valve showed effective performance, with low pressure gradients, indicating good blood flow, and a high percentage experiencing no patient-prosthesis mismatch.
  • While the short-term results are promising with no significant complications reported, further long-term studies comparing it to other valves are necessary to evaluate its effectiveness over time.
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Background: Due to a considerable rise in bioprosthetic as opposed to mechanical valve implantations, an increase of patients presenting with failing bioprosthetic surgical valves in need of a reoperation is to be expected. Redo surgery may pose a high-risk procedure. Transcatheter aortic valve-in-valve implantation is an innovative, less-invasive treatment alternative for these patients.

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