Publications by authors named "M Wollweber"

Article Synopsis
  • SLOT (Scanning Laser Optical Tomography) is an advanced imaging technique that faces challenges due to difficulties in matching the refractive indexes (RIs) of samples and their surrounding media, affecting image quality.
  • The study aims to lessen the challenges of RI matching by developing a post-processing correction method to fix errors in SLOT measurements caused by mismatched RIs.
  • Simulations and experiments show that while RI mismatches can severely degrade image quality, applying the correction method can significantly improve results even with RIs mismatched by up to 0.1, demonstrating a promising approach for enhancing SLOT imaging.
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Electrospun polycaprolactone:gelatin (PCL:GT) fibre scaffolds are widely employed in the field of tissue implants. Here, the orientation of fibres plays an important role in regard to implantation due to the impact on the mechanical properties. Likewise, the orientation of collagen fibres in skin tissue is relevant for dermatology.

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Electrospun fiber scaffolds are gaining in importance in the area of tissue engineering. They can be used, for example, to fabricate graded implants to mimic the tendon bone junction. For the grading of the tensile strength of the fiber scaffolds, the orientation of the fibers plays a major role.

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Currently, many optical modalities are being investigated, applied, and further developed for non-invasive analysis and sensing in the life sciences. To befit the complexity of the study objects and questions in this field, the combination of two or more modalities is attempted. We review our work on multimodal sensing concepts for applications ranging from non-invasive quantification of biomolecules in the living organism to supporting medical diagnosis showing the combined capabilities of Raman spectroscopy, optical coherence tomography, and optoacoustics.

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In this article, we present a simple and intuitive approach to create a handheld optoacoustic setup for near field measurements. A single piezoelectric transducer glued in between two sheets of polymethyl methacrylate (PMMA) facilitates nearfield depth profiling of layered media. The detector electrodes are made of indium tin oxide (ITO) which is both electrically conducting as well as optically transparent, enabling an on-axis illumination through the detector.

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