Electrons in polar liquids give rise to a polaron resonance at a terahertz (THz) frequency ν_{0} depending on electron concentration. The impact of this resonance on light propagation is studied in experiments, where a femtosecond pump pulse generates electrons via multiphoton ionization and a THz probe pulse propagated through the excited sample is detected in a phase-resolved way. We observe a behavior characteristic for ϵ-near-zero materials with strongly modified phase and group velocities around ν_{0}, and a broadening of the THz pulse envelope below ν_{0}.
View Article and Find Full Text PDFMyelin loss induces neural dysfunction and contributes to the pathophysiology of neurodegenerative diseases, injury conditions, and aging. Because remyelination is often incomplete, better understanding endogenous remyelination and developing remyelination therapies that restore neural function are clinical imperatives. Here, we use in vivo two-photon microscopy and electrophysiology to study the dynamics of endogenous and therapeutic-induced cortical remyelination and functional recovery after cuprizone-mediated demyelination in mice.
View Article and Find Full Text PDFThe nonlinear polaronic response of electrons solvated in liquid 2-propanol is studied by two-dimensional terahertz spectroscopy. Solvated electrons with a concentration of c_{e}≈800 μM are generated by femtosecond photoionization of alcohol molecules. Electron relaxation to a localized ground state impulsively excites coherent polaron oscillations with a frequency of 3.
View Article and Find Full Text PDFObjective: Femoral head necrosis (FHN) affects mostly young and active people. The most common operative therapy is core decompression (CD) with optional cancellous bone grafting (CBG). Because little information is available on the long-term results of these procedures, we investigated the effectiveness of CD and CD + CBG in patients with ARCO stage II FHN in terms of postoperative pain, range of motion, patient-reported outcome measures (Harris Hip Score, Hip Disability and Osteoarthritis Outcome Score, EuroQol 5D, and Short Form 36 Questionnaire), and disease progression.
View Article and Find Full Text PDFBackground: Avascular osteonecrosis of the femoral head (AVN) often results in total hip arthroplasty (THA). The cause for increased THA revision rates among patients with AVN is not yet fully understood.
Purpose: To perform a comparative radiological analysis of implant integration between patients with AVN and osteoarthritis (OA).