Publications by authors named "M Witkowska"
The research presented in this paper is part of a larger project concerning high-manganese alloys with different chemical compositions (mainly in manganese content from 21 to 31 wt.%). The presented examination results concern the analysis of the microstructure and textures in high-manganese X85MnAl29-9 steel, an age-hardenable steel, during aging at 550 °C for various times.
View Article and Find Full Text PDFPurpose: Polydopamine nanoparticles (PDA NPs) have great potential in medicine. Their applications being widely investigated in cancer therapy, imaging, chemotherapy, photodynamic therapy (PDT), photothermal therapy (PTT), and tissue repair. The aim of our study was to assess the in vivo toxicity and changes in oxidative stress biomarkers in organs of animals treated with mesoporous PDA NPs modified with iron (MPDAFe NPs), coated with the cancer cell membrane and loaded with doxorubicin (DOX), and subsequently subjected to PTT.
View Article and Find Full Text PDFBackground: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome with various etiologies. Its treatment is complicated by several important but not immediately obvious issues (e.g.
View Article and Find Full Text PDFArticle Synopsis
- Herpes simplex virus (HSV) encephalitis is a serious neurological condition that can lead to temporal lobe damage and result in seizures and psychiatric symptoms, particularly affecting older adults.
- A case study involving an older male patient revealed that he had new visual hallucinations and seizures, which led to a diagnostic journey that included CT and EEG tests, ultimately suggesting HSV encephalitis despite negative PCR results for the virus.
- The patient improved significantly with antiviral and antiepileptic treatments, highlighting the importance of recognizing potential underlying causes of acute neuropsychiatric symptoms for timely and effective intervention.
Introduction: Chronic lymphocytic leukemia (CLL) is one of the most common types of leukemia in adult patients. The landscape of CLL therapy has changed in the last decades with the introduction of antibody-based therapies and novel targeted agents resulting in improved outcomes.
Areas Covered: This article describes the use of monoclonal antibodies, bispecific antibodies and antibody-drug conjugates in the treatment of relapsed and refractory CLL.