Publications by authors named "M Wilkes"
Background: Institutional Review Boards (IRBs) in the United States play a crucial role in ensuring the ethical conduct of clinical trials, including assessing the scientific merit of studies to justify the risks to participants. However, prior research suggests that many IRBs do not systematically evaluate scientific merit, raising concerns about the approval of low-quality trials.
Objective: To investigate whether IRBs provide adequate guidance on assessing scientific merit in their Standard Operating Procedures (SOPs) and other relevant materials.
A Multicenter Prospective Cohort Study of Antibiotics for OnabotulinumtoxinA.
Urogynecology (Phila)
December 2024
Importance: Urinary tract infection (UTI) is the most common complication of intradetrusor onabotulinumtoxinA (BTX-A) injection. Despite this, there are no evidence-based guidelines on antibiotic prophylaxis.
Objectives: Our primary aim was to determine whether antibiotic prophylaxis decreased symptomatic, culture-proven UTI rates within 6 weeks of intradetrusor BTX-A injection.
Article Synopsis
- Microalgae, particularly Chlorella vulgaris, are being studied as health-boosting feed additives in aquaculture, specifically for Atlantic salmon, due to their ability to enhance immune function and manage stress responses.
- In the study, salmon were fed diets with varying levels of C. vulgaris and showed improved feed conversion and protein retention, with notable changes in gut microbial diversity and composition after feeding on higher amounts of the algae.
- Exposure to a stressor (peracetic acid) revealed that fish on higher algae diets exhibited less transcriptional stress response and increased antioxidant protein levels, suggesting that C. vulgaris may help mitigate stress effects in aquatic species.
The COVID-19 pandemic, patient preference, and economic opportunity are shifting acute care from the hospital to the home, supported by the transformation in remote monitoring technology. Monitoring patients with digital medical devices gives unprecedented insight into their physiology. However, this technology does not exist in a vacuum.
View Article and Find Full Text PDFBackground: Walking catfish, Clarias batrachus is one of the native and most popular freshwater catfish species in Indonesia. However, cultivation faces challenges, particularly due to the scarcity of larvae resulting from underdeveloped breeding technologies. Cryopreservation is a method of storing sperm to maintain viability for a long period and support the breeding technology of the fish.
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