Photocatalytic PPh-Mediated Synthesis of C3-Functionalized Indoles via Radical Annulation of Nitroarenes and Alkenes.

Oxidatively generated phosphine radical cations are reactive intermediates that can be used for the generation of carbon and heteroatom centered radicals via deoxygenation processes. Such P-radical cations can readily be generated via single electron transfer oxidation using a redox catalyst. Cheap and commercially available nitroarenes are ideal nitrogen sources for the construction of organic amines and N-containing heterocycles.

Metal-free photosensitized radical relay 1,4-carboimination across two distinct olefins.

Intermolecular carboamination of olefins offers a powerful platform for the rapid construction of structurally complex amines from abundant feedstocks. However, these reactions often require transition-metal catalysis, and are mainly limited to 1,2-carboamination. Herein, we report a novel radical relay 1,4-carboimination across two distinct olefins with alkyl carboxylic acid-derived bifunctional oxime esters energy transfer catalysis.

Therapeutic alliance and behavior inhibition.

Abstract The study examined whether the quality of the therapeutic alliance is associated with a tendency toward behavior inhibition. Inhibition was measured by the frequency with which the clients used the word "not" and by their verbal productivity. In treatment sessions with low-quality therapeutic alliance, clients tended to use the word "not" more often and speak fewer words.

European isolation and confinement study. Cognitive fatigue in complex decision-making.

In six healthy males, confined in a hyperbaric chamber complex for 4 weeks, mental fatigue was assessed by means of a Working Memory Test. This test involved a decision-making task, which concerned the management of the chemical environment of a spacecraft affected by the presence of contaminants. Five items of reference information were shown on a screen and had to be memorized, then five "status" cards were given, upon which the need for corrective action had to be decided.

Assessing the impact of computer workload on operator stress: the role of system controllability.

This paper considers the impact of working with computer-based systems in terms of mental workload and the well-being of operators. In particular, the paper focuses on issues of controllability in human-computer systems as they relate to operator stress. Through the adoption of a state control model of stress regulation, it becomes apparent that while general usability criteria are necessary for the design of controllable systems, they may not be sufficient to guarantee controllability.