Is Day-4 morula biopsy a feasible alternative for preimplantation genetic testing?

Objective: To assess the efficacy and clinical outcome of PGT-M undertaken on Day-3, Day-4 and Day-4 "delayed" embryos that were unsuitable for biopsy on Day-3.

Design And Setting: Cohort-historical study of all consecutive patients admitted to the IVF-PGT-M program in a large tertiary center.

Main Outcome Measure(s): The pregnancy rates and the percentages of complete, incomplete diagnosis, PCR failure, abnormal embryos in PGT of Day-3 cleavage-stage, Day-4 and Day-4 "delayed" embryos.

Depression and anxiety in elderly patients with severe symptomatic aortic stenosis persistently improves after transcatheter aortic valve replacement (TAVR).

Introduction: Data on the prevalence of depression and anxiety in elderly cardiovascular disease patients are limited and there are only few studies focussing on treatment effects. Thus, the current study aimed to analyse elderly patients suffering from aortic stenosis (AS) and undergoing transcatheter aortic valve replacement (TAVR) with respect to both, prevalence rates before TAVR and dynamics in the clinical course.

Methods: The study included 140 AS patients undergoing TAVR (77.

Surgical outcomes after pediatric kidney transplantation at the University of Heidelberg.

Background: Kidney transplantation (KTx) is the treatment of choice for children with end-stage renal disease (ESRD).

Objective: An update of 48 years of surgical experience with pediatric KTx (PKTx) is presented, and the results between recipients of organs from deceased donors (DDs) and living donors (LDs) are compared.

Study Design: All patients younger than 18 years who underwent KTx between 1967 and 2015 were evaluated.

Optically transparent solid electrodes for precision Penning traps.

We have conceived, built, and operated a cryogenic Penning trap with an electrically conducting yet optically transparent solid electrode. The trap, dedicated to spectroscopy and imaging of confined particles under large solid angles, is of "half-open" design with one open endcap and one closed endcap that mainly consists of a glass window coated with a highly transparent conductive layer. This arrangement allows for the trapping of externally or internally produced particles and yields flexible access for optical excitation and efficient light collection from the trapping region.

Superconducting radio-frequency resonator in magnetic fields up to 6 T.

We have measured the characteristics of a superconducting radio-frequency resonator in an external magnetic field. The magnetic field strength has been varied with 10 mT resolution between zero and 6 T. The resonance frequency and the quality factor of the resonator have been found to change significantly as a function of the magnetic field strength.