Publications by authors named "M Wierzchowiecki"

Heparin-induced thrombocythopenia (HIT) is a potentially serious complication of heparin treatment, rarely observed in cardiological wards. We present a case of a 38-year-old woman with dilated cardiomyopathy and massive pulmonary embolism treated with alteplase and unfractionated heparin. On 12th day an unexpected fall in platelet count was observed, without new signs of thrombosis.

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Article Synopsis
  • Heart rate turbulence (HRT) is influenced by the baroreceptor reflex and may indicate autonomic dysfunction, particularly after myocardial infarction, though its role in chronic heart failure (CHF) is less clear.
  • The study analyzed 64 CHF patients, measuring HRT parameters (turbulence onset and turbulence slope) alongside uric acid and brain natriuretic peptide levels, and followed up over 6 and 12 months.
  • Results revealed that CHF patients had significantly worse HRT parameters compared to healthy controls, with correlations found between HRT metrics, NYHA class, and biochemical markers, suggesting that HRT could serve as a valuable prognostic tool in CHF management.
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Unlabelled: Coronary artery disease (CAD) in women remains a difficult diagnostic problem. The usefulness of exercise electrocardiography (EXT) in these patients is limited. The value of other noninvasive tests including Tc99m-MIBI single photon emission computed tomography (SPECT), is still to be determined.

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Background: Heart rate turbulence (HRT) assessment is used as noninvasive method based on physiological sinus node response to the premature ventricular beat. Blunted HRT may indicate the autonomic nervous system impairment and can be helpful in identifying high-risk patients. Obstructive sleep apnea syndrome (OSAS) leads to cardiovascular complications.

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Background: In patients with type 1 diabetes mellitus (DM) impairment of the coronary circulation has been observed. This phenomenon could be ascribed to the existence of a specific cardiomyopathy. Disturbances in other microcirculation beds--renal and ocular--are mirrored by microalbuminuria and retinopathy, respectively.

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