Publications by authors named "M Wieghart"

Article Synopsis
  • Over the past five years, research on transgenic pigs focused primarily on improving their growth performance, but side effects from overexpressed growth hormone (GH) have been noted.
  • Researchers developed a new strategy to regulate GH expression by using a liver-specific sequence linked to the bovine GH gene, resulting in the creation of 124 pig offspring, 7 of which were confirmed transgenic.
  • These transgenic pigs showed significant changes in fat characteristics, such as a 41% reduction in backfat thickness compared to controls, and further studies on gene expression regulation and characterization are ongoing.
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One dry and four lactating Holstein cows were prepared with chronic catheters in the mesenteric, hepatic and portal veins and used to study glucose absorption and hepatic gluconeogenesis. The dry cow was used in a preliminary assessment of the methods. In the main experiment high concentrate and high forage diets, providing equal energy intake, were delivered in hourly portions from an automatic feeder as total mixed rations.

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