Publications by authors named "M Welter"
Glycated albumin (GA) serves as a biomarker for short-term glycemic control (2-3 weeks), playing a role in diabetes management. Our goal was to establish reference intervals (RIs) for serum GA, and the ratios of 1,5-anhydroglucitol to GA (AGI) and GA to HbA1c in a Euro-Brazilian pediatric population (10 y, n = 299), adults (43.5 y; n = 290), and pregnant women (26 y, n = 406; 26.
View Article and Find Full Text PDFObjective: To investigate the effects of directional subthalamic deep brain stimulation (STN-dDBS) on gait and balance disorders, including freezing of gait (FOG), in patients with advanced Parkinson's disease (PD).
Methods: We included 10 participants who underwent STN-DBS and presented severe preoperative FOG, in a randomized, double-blind, crossover study. We used segmented DBS electrodes to investigate whether directing the predicted volume of tissue activated (VTA) to overlap the central STN preferentially improved gait and balance disorders compared to directional DBS applied in the more posterior STN (sensorimotor).
Article Synopsis
- * It found that GTS patients exhibited higher firing rates and burst activity, while DYS patients showed more pauses and burst frequency, highlighting distinct neuronal activity patterns between the two disorders.
- * The research suggests a need for further studies on neuronal behavior in the GPi to improve DBS techniques and tailor treatments for better clinical outcomes in patients with hyperkinetic movement disorders.
Revision Surgery With Refixation After Mandibular Fractures.
Craniomaxillofac Trauma Reconstr
September 2024
Study Design: Retrospective, descriptive observational study.
Objective: The need for revision surgery after mandibular fractures is an indicator for severe postoperative complications. This study aimed to characterise this patient cohort, describe solutions to deal with complications and evaluate treatment quality as a risk variable for complications.
Article Synopsis
- - The study investigated changes in biological, clinical, and imaging markers in carriers of spinocerebellar ataxia (SCA) types 2 and 7 over one year, focusing on MRI and neurofilament light chain (NfL) levels.
- - It included assessments of neurological function, quality of life, and brain imaging among 15 SCA2 carriers, 15 SCA7 carriers, and 10 control subjects, while noting differences in SARA scores and brain volume from baseline measurements.
- - Results indicated significant brain volume loss and worsening motor function in SCA2 carriers, an increase in SARA scores and thinning of retinal layers in SCA7, highlighting the progressive nature of these at