Publications by authors named "M Weder"
Background: Post-lung transplantation (LTx) fluid accumulation can lead to dilution of serum creatinine (SCr). We hypothesized that fluid accumulation might impact the diagnosis, staging, and outcome of posttransplant acute kidney injury (AKI).
Methods: In this retrospective study, we analyzed data from 131 adult LTx patients at a single German lung center between 2005 and 2018.
The dietary approach to stop hypertension (DASH) diet combines the antihypertensive effect of a low sodium and high potassium diet. In particular, the potassium component of the diet acts as a switch in the distal convoluted tubule to reduce sodium reabsorption, similar to a diuretic but without the side effects. Previous trials to understand the mechanism of the DASH diet were based on animal models and did not characterize changes in human ion channel protein abundance.
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- - HempChoice® Hemp Oil Extract is a hemp-derived product mostly containing 55-75% cannabidiol (CBD) along with other cannabinoids and terpenes, with no significant safety concerns shown in multiple studies.
- - Safety studies, including a 90-day trial, revealed that the extract was well tolerated with no serious side effects, and any minor changes observed were considered temporary and reversible.
- - The extract's no observed adverse effect level (NOAEL) was established at 185.90 mg/kg body weight/day based on testing in Sprague-Dawley rats, indicating a safe threshold for consumption.
Extracellular vesicles (EVs) are promising novel cellular communicators and biomarkers in acute kidney injury (AKI). These submicron vesicles derive from all cell types along the urinary tract and reflect molecular processes of their parent cells and physiological and pathological conditions in AKI. Several EV protein and RNA biomarker candidates have been identified.
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