The impact of vitrectomy on outcomes achieved with 0.19 mg fluocinolone acetonide implant in patients with diabetic macular edema.

Background: There is a lack of consensus on the use of intravitreal corticosteroid therapies in patients with diabetic macular edema (DME) and prior vitrectomized eyes in clinical practice.

Methods: Retro-IDEAL was a 3-year retrospective, multicenter study in patients with chronic DME (i.e.

Three-year results from the Retro-IDEAL study: Real-world data from diabetic macular edema (DME) patients treated with ILUVIEN (0.19 mg fluocinolone acetonide implant).

Introduction: The Retro-IDEAL (ILUVIEN Implant for chronic DiabEtic MAcuLar edema) study is a retrospective study designed to assess real-world outcomes achieved with the ILUVIEN® (0.19 mg fluocinolone acetonide (FAc)) in patients with chronic diabetic macular edema (DME) in clinical practices in Germany.

Methods: This study was conducted across 16 sites in Germany and involved 81 eyes (63 patients) with persistent or recurrent DME and a prior suboptimal response to a first-line intravitreal therapy (primarily anti-VEGF intravitreal therapies).

Performance of complex snow cover descriptions in a distributed hydrological model system: A case study for the high Alpine terrain of the Berchtesgaden Alps.

[1] Runoff generation in Alpine regions is typically affected by snow processes. Snow accumulation, storage, redistribution, and ablation control the availability of water. In this study, several robust parameterizations describing snow processes in Alpine environments were implemented in a fully distributed, physically based hydrological model.