Digital Determinants: The Inclusion of Social Media in Health Conceptualization.

Social determinants of health (SDOH) are vital components to helping address health equity and the social and economic factors that impact health and health outcomes. Two important aspects of SDOH to consider are informational access and accuracy. In an era increasingly influenced by digital platforms, this study delves into the significant role of social media as an SDOH.

Factors Associated With Decision to Use and Dosing of Sugammadex in Children: A Retrospective Cross-Sectional Observational Study.

Background: Sugammadex was initially approved for reversal of neuromuscular blockade in adults in the United States in 2015. Limited data suggest sugammadex is widely used in pediatric anesthesia practice however the factors influencing use are not known. We explore patient, surgical, and institutional factors associated with the decision to use sugammadex versus neostigmine or no reversal, and the decision to use 2 mg/kg vs 4 mg/kg dosing.

Novel determinants of NOTCH1 trafficking and signaling in breast epithelial cells.

The evolutionarily conserved Notch signaling pathway controls cell-cell communication, enacting cell fate decisions during development and tissue homeostasis. Its dysregulation is associated with a wide range of diseases, including congenital disorders and cancers. Signaling outputs depend on maturation of Notch receptors and trafficking to the plasma membrane, endocytic uptake and sorting, lysosomal and proteasomal degradation, and ligand-dependent and independent proteolytic cleavages.

Prevalence and Factors Associated with Zero-Dose Children amongst Nomadic and Non-Nomadic Fulani in Yobe State, North-East Nigeria.

Background: Immunization is a very cost-effective and readily available intervention capable of preventing Vaccines Preventable Diseases (VPDs). This study aimed to identify and compare the prevalence and factors associated with zero-dose immunization status among children of nomadic and non-nomadic Fulani in Yobe State, North-East Nigeria.

Methodology: A comparative cross-sectional design was used to study 348 nomadic, and 345 non-nomadic under-five children, selected using a multi-staged sampling technique.