Consensus on a Patient-Centered Definition of Atopic Dermatitis Flare.

Importance: Flare is a term commonly used in atopic dermatitis (AD) care settings and clinical research, but little consensus exists on what it means. Meanwhile, flare management is an important unmet research and treatment need. Understanding how various therapies might comparatively improve AD flares as a measure of treatment effectiveness may facilitate shared decision-making and enable assessment of effectiveness within and outside clinical settings.

Towards a patient-centred definition for atopic dermatitis flare: a qualitative study of adults with atopic dermatitis.

Background: The term 'flare' is used across multiple diseases, including atopic dermatitis (AD), to describe increased disease activity. While several definitions of an AD flare have been proposed, no single definition of AD flare is widely accepted and it is unclear what the term 'AD flare' means from the patient perspective.

Objectives: To understand AD flares from the adult patient perspective and to explore how adults with AD define an AD flare.

The effects of anti-hypertensive medication on learning and memory.

1. The aim of the study was to investigate whether there were differential effects of three different anti-hypertensive medications (cilazapril, atenolol, nifedipine) on cognitive function. 2.

Coloured speech perception: is synaesthesia what happens when modularity breaks down?

Evidence was reported earlier from a single case that chromatic-lexical (CL) synaesthesia was a genuine phenomenon. A study is presented in which nine subjects were tested who also reported having coloured hearing. The following questions were addressed: (a) were these cases also genuine (ie consistent over time), (b) were they truly lexical, or rather variants of this condition, such as chromatic-graphemic (CG) or chromatic-phonemic (CP) synaesthesia, (c) did the experimental subjects show any commonalities between them, and (d) were they able to give information on a standard questionnaire about the phenomenology and ontogenesis of the condition? Subjects were asked to describe the colour sensation experienced on hearing items from a list of 130 words, phrases, and letters.

The Maudsley Mentation test: a method for extended monitoring of mental status after aneurysmal subarachnoid hemorrhage.

A new scale for the repeated, rapid assessment of mental function in patients with subarachnoid hemorrhage is described. Its reproducibility is evaluated and early experience with its use in the intended clinical setting is reported. The test (Maudsley Mentation Test) proved to be more sensitive to fluctuations in cerebral functioning than existing measures of conscious level, and the results were reproducible among observers with different backgrounds (surgeons, nurses, and psychologists).