Glenn circulation causes early and progressive shunting in a surgical model of pulmonary arteriovenous malformations.

Pulmonary arteriovenous malformations (PAVMs) universally develop in patients with single ventricle congenital heart disease. Single ventricle PAVMs have been recognized for over 50 years but remain poorly understood. To improve our understanding, we developed a surgical rat model of Glenn circulation and characterized PAVM physiology over multiple time points.

Comparison of the outcomes of Total Knee Arthroplasty (TKA): tourniquet and tourniquet-less arthroplasty.

Total knee replacement surgery (TKA) ranks among the most commonly performed orthopedic procedures nowadays. Many surgeons perform TKA with the use of tourniquet. It is also possible to carry out a tourniquet-less TKA.

CPAP complications after dacryocystorhinostomy: a narrative review.

Study Objectives: Patients with obstructive sleep apnea often require the use of a continuous positive airway pressure (CPAP) machine. However, some patients experience issues using CPAP after receiving a dacryocystorhinostomy (DCR) for epiphora. This review aims to assess these complications and the potential interventions.

Repeated seizure-induced brainstem neuroinflammation contributes to post-ictal ventilatory control dysfunction.

Patients with epilepsy face heightened risk of post-ictal cardiorespiratory suppression and sudden unexpected death in epilepsy (SUDEP). Studies have shown that neuroinflammation, mediated by the activation of microglia and astrocytes, may be a cause or consequence of seizure disorders. Kcnj16 (Kir5.

Endoscopic endonasal obliteration of the frontal recess and anterior skull base.

Background: Although endoscopic techniques have become more widespread in repair of frontal sinus (FS) defects, certain pathologies still require open approach (extensive trauma or tumors). Under certain circumstances even multiple complex open reconstructive procedures might fail to resolve persistent pneumocephalus or CSF leak and subsequently surgeons tend to escalate the invasiveness and employ even more complex and aggressive approaches. We present our experience treating persistent pneumocephalus or CSF leak after previously failed transcranial reconstruction utilizing an endoscopic endonasal approach (EEA).