Unveiling the role of rubber seals in the generation of decentralized disinfection by-products in chlorinated water distribution systems.

The degradation of rubber seal (RS), particularly ethylene-propylene-diene (EPDM), in the drinking water networks has been confirmed, yet the role of RS as a disinfection by-product (DBP) precursor remains unknown. This study provides explicit proof of the formation of halogenated disinfection by-products (X-DBPs) from RS in chlorinated drinking water within water supply systems. Over time, exposure to chlorinated water ages RS, releasing high levels of organic compounds, which act as DBP precursors.

Enhancement of cannabidiol oral bioavailability through the development of nanostructured lipid carriers: In vitro and in vivo evaluation studies.

Cannabidiol (CBD) is a natural product isolated from the Cannabis sativa plant that was approved by the United States Food and Drug Administration (US FDA) for the treatment of resistant epilepsy. Despite its therapeutic potential, CBD's clinical application is limited by its poor aqueous solubility and low oral bioavailability. The primary aim of this research was to enhance the aqueous solubility and oral bioavailability of CBD by developing nanostructured lipid carriers (NLCs) using conventional hot homogenization method (CHH).

Scanning of antennae and maxillary palps of anthropophilic and ornithophilic as potential arbovirus vectors.

Background And Aim: Efficient mosquito vectors are required to persist and propagate arthropod-borne diseases that seriously affect impoverished populations worldwide. Mosquito sensilla plays a crucial role in host-seeking and disease transmission to humans. This study aimed to distinguish between the several types of sensilla found on the antennae and maxillary palps of and , matching this diversity with host preference and disease transmission.

Diffuse Type Pancreatic Ductal Adenocarcinoma: The Linitis Plastica Type of the Pancreas.

Pancreatic malignant tumors are diverse and characterized by aggressive nature with high mortality rates. Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic malignant tumors and accounts for approximately 90% of pancreatic malignancies. A subtype of PDAC, diffuse type PDAC (DTP), is a very rare and underreported tumor, known for its aggressive traits.